648907-28-2Relevant academic research and scientific papers
Newer substituted benzoxazepinyl-quinazolinones as potent antipsychotic and anticonvulsant agents
Bajaj, Kiran,Srivastava, Virendra Kishor,Kumar, Ashok
, p. 480 - 485 (2007/10/03)
3-Amino-[2′-substitutedaryl- 3′substitutedarylaminomethylene-2′,3′-dihydro- 1′,5′- benzoxazepin- 4′-yl]- 2- methyl-quinazolin- 4(3H)- ones 11-18 and 3-amino[2′-substituted aryl-3′-substitutedarylazo-2′,3′-dihydro-1′, 5′-benzoxazepin-4′-yl]-2-methyl-quinazolin-4(3H)-ones 19-26 were synthesized from 3-amino-[2′-substitutedaryl-2′,3′- dihydro-1′,5′-benzoxazepin-4′-yl]-2-methyl- quinazolin-4(3H)-ones 7-10 by Mannich's reaction and by diazotisation, respectively, on the 3rd position of the benzoxazepine ring of the compounds 7-10. The newly synthesized compounds showed potent antipsychotic and anticonvulsant activities.
