64923-68-8

Upstream product

• 1570-95-2 2-phenylpropane-1, 3-diol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 957131-04-3 2-phenylpropane-1,3-diazide 
• 25636-61-7 2-phenyl-1,3-propanedithiol 
• 6133-92-2 4-Phenyl-1,2-dithiolane 
• 1397685-18-5 5-phenyl-1,3-dithiane 
• 873977-00-5 N,N'-(2-phenylpropane-1,3-diyl)diacetamide 
• 55165-09-8 1,3-diamino-2-phenylpropane 
• 957131-05-4 N-(3-amino-2-phenylpropyl)acetamide 
• 957131-07-6 (R)-allyl (3-amino-2-phenylpropyl)carbamate 
• 125836-30-8 3-phenyl-N-(p-tolyl)azetidine 

Relevant academic research and scientific papers

Carbon-carbon bond cleavage in fluorescent pyronin analogues induced by yellow light

A novel class of pyronin analogues, which undergoes a photochemically induced cleavage of the C-C bond in the presence of water in both solution and on a silica gel surface upon direct irradiation with visible light, is reported. The reaction course can be monitored by characteristic fluorescence of both the starting compound and the final product. This system could find useful applications in the field of photoremovable protecting groups or caged fluorophores.

Enzymatic desymmetrization of prochiral 2-substituted-1,3-diamines: Preparation of valuable nitrogenated compounds

A wide range of prochiral 1, 3-diamines were first efficiently synthesized and subsequently desymmetrized by using lipase from Pseudomonas cepacia as catalyst and diallyl carbonate as alkoxycarbonylating agent. In all cases, the amino carbamates of R-configuration were recovered. Final selective cleavage of the N-allyloxycarbonyl moiety was carried out under mild reaction conditions, which demonstrates the high versatility and potential of this chemoenzymatic route as a source of intermediates in the synthesis of related optically active nitrogenated derivatives.

First desymmetrization of 1,3-propanediamine derivatives in organic solvent. Development of a new route for the preparation of optically active amines

The chemical synthesis and enzymatic desymmetrization of a panel of prochiral diamines have been successfully described for the first time using lipases in organic solvents. A family of 2-aryl-1,3-propanediamines has been obtained with high enantiopurity and good yields in the PSL-catalyzed reaction using diallyl carbonate in 1,4-dioxane.