64944-80-5

Upstream product

• 13636-88-9 3,3-bis(methylthio)-1-phenylprop-2-en-1-one 
• 107-15-3 ethylenediamine 
• 81471-31-0 3-oxo-3-phenyl-propionimidic acid ethyl ester; hydrochloride 
• 32188-99-1 2-phenacylthioimidazoline 
• 70-11-1 α-bromoacetophenone 
• 37510-42-2 3,3-bis(ethylthio)-1-phenylprop-2-en-1-one 
• 100-42-5 styrene 
• 887144-94-7 Togni's reagent II 
• 614-16-4 Benzoylacetonitrile 

Downstream Products

• 118792-71-5 (7-Benzoyl-5-oxo-2,3,5,6-tetrahydro-1H-pyrrolo[1,2-a]imidazol-6-yl)-acetic acid 
• 138963-28-7 2-imidazolidine 
• 132111-56-9 3-benzoyl-5,6-dihydro-4H-imidazo<1,2-c><1,2,3>triazole 
• 132111-44-5 1-(p-chlorophenyl)-4-(2-imidazolinyl)-5-phenyl-1,2,3-triazole 
• 132111-40-1 1-(p-nitrophenyl)-4-(2-imidazolinyl)-5-phenyl-1,2,3-triazole 
• 132111-52-5 1-(p-methoxyphenyl)-4-(2-imidazolinyl)-5-phenyl-1,2,3-triazole 
• 112030-65-6 2-Phenacyl-4,5-dihydro-1H,3H-imidazolium chloride 
• 115859-60-4 2-<1-benzoyl-2-phenylethylidene>imidazolidine 
• 115859-85-3 7-benzoyl-1,2,3,6-tetrahydro-5H-pyrrolo<1,2-a>imidazol-5-one 
• 115859-73-9 ethyl 3-benzoyl-3-(2-imidazolidinylidene)propionate 
• 136271-12-0 2-Imidazolidin-2-ylidene-2-(2-nitro-phenylazo)-1-phenyl-ethanone 
• 107165-93-5 8-benzoyl-2,3,6,7-tetrahydroimidazo<1,2-a>pyridin-5(1H)-one 
• 107165-85-5 methyl 4--(E)-but-2-enoate 
• 107165-95-7 methyl 8-benzoyl-1,2,3,5-tetrahydro-5-oxoimidazo<1,2-a>pyridine-7-carboxylate 

Relevant academic research and scientific papers

Direct Access to α-Oxoketene Aminals via Copper-Catalyzed Formal Oxyaminalization of Alkenes under Mild Conditions

A copper-catalyzed four-component formal oxyaminalization of alkenes with Togni's reagent and amines using molecular oxygen as both the oxidant and oxygen source has been developed for the first time, offering a straightforward and efficient method for the synthesis of a range of structurally diverse α-oxoketene aminals. The use of cheap copper catalyst and readily available substrates, excellent functional group tolerance, broad substrate scope, mild conditions, and simple procedure are the attractive features of the strategy.

Multicomponent Cascade Reaction by Metal-Free Aerobic Oxidation for Synthesis of Highly Functionalized 2-Amino-4-coumarinyl-5-arylpyrroles

A novel approach has been constructed for the synthesis of two types of 2-amino-4-coumarinyl-5-arylpyrroles (ACAPs, 5 and 6) through a cascade reaction and a metal-free catalyzed aerobic oxidation reaction of arylglyoxal monohydrates 1, 1,1-enediamines (E

Synthesis of Partially Reduced Imidazo[1,2- a ]pyridines through an Unprecedented Base-Mediated (4+2) Cyclization

A water-mediated regioselective synthesis of 6,7-diaryl-5-oxo-2,3,5,6-tetrahydroimidazo[1,2-a]pyridine-6-carbonitriles was performed by the reaction of 2-[1-cyano-2,2-bis(methylsulfanyl)vinyl]benzonitrile with 1-aryl-2-(imidazolidin-2-ylidene)ethanones un

Synthesis of imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines in water and their snar cyclizations

Synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydropyrido[1,2-a] pyrimidines by a one-pot and three component reaction of α-oxoketenedithioacetals, diamines and DMAD in water has been described. Different routes for accessing the desired compoun

Three-component synthesis of indanone-fused spirooxindole derivatives

A simple, straightforward and versatile multicomponent protocol for the synthesis of indanone-fused spirooxindole derivatives has been developed. The strategy involves the one-pot three-component reaction of heterocyclic ketene aminals, 1H-indene-1,3(2H)-

Convenient synthesis of perfluoroalkyl substituted 2-oxopyridine-fused 1,3-diazaheterocycles via a one-pot three-component reaction

An efficient one-pot synthesis of perfluoroalkylated ring-fused 2-pyridones by three-component reaction of diamine, ketene dithioacetal, and methyl 2-perfluoroalkynoate in EtOH is reported. This protocol has the advantages of easiness, higher yields, and

Regioselective synthesis of heterocyclic ketene N,N-,N,O-and N,S-acetals in aqueous medium

The reactions of ketene dithioacetals with ethane-1,2-diamine, propane-1,3-diamine, 2-aminoethanol, 3-aminopropanol, and 2-aminoethanethiol in ordinary water in the absence of any acid/base catalyst afforded the heterocyclic ketene N,N-, N,O-and N,S-aceta

Synthesis of annelated [a]aza-anthracenones and thieno[3,2-g]aza- naphthalenones through ring transformation of 2H-pyran-2-one followed by photocyclization

A concise synthesis of some new classes of heterocycles (4-aryl-11-oxo-1,2,3,11-tetrahydro-1,3a-diaza-cyclopenta[a]anthracen-6- carbonitriles and 5-aryl-12-oxo-1,3,4,12-tetrahydro-2H-1,4a-diazabenzo[a] anthracene-7-carbonitriles) has been developed by the

A new protocol for the synthesis of N(1)-unsubstituted 2-substituted 2 imidazolines

Lateral metallation at C-2(α) of 1-tert-butoxycarbonyl-2-methyl-2- imidazoline followed by reaction with a range of C-electrophiles and deprotection with TFA reliably affords N(1)-unsubstituted 2-substituted 2- imidazolines; P- or Se-electrophiles lead to 2-alkenyl-2-imidazolines via Wadsworth-Emmons or selenoxide elimination protocols. (C) 2000 Elsevier Science Ltd.

A new route to 3H-1,5-benzodiazepines and heterocyclic ketene animals from benzoyl substituted ketene dithioacetals and diamines

Heterocyclic ketene aminals 5 or 3H-1,5-benzodiazepines 4 were obtained from the reaction of benzoyl substituted ketene dithioacetals 1 with various diamines 2. The mechanism of formation of these two different products are discussed.