64951-04-8

Basic information

• Product Name: ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
• Synonyms: Ethyl imidazo[2,1-b][1,3]thiazole-6-carboxylate 97%;Ethyl imidazo[2,1-b]thiazole-6-carboxylate;6-(Ethoxycarbonyl)imidazo[2,1-b][1,3]thiazole;Ethylimidazo[2,1-b][1,3]thiazole-6-carboxylate97%;IMIDAZO[2,1-B]THIAZOLE-6-CARBOXYLIC ACID ETHYL ESTER;ETHYL IMIDAZO[1,2-A]THIAZOLE-6-CARBOXYLATE;ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
• CAS NO: 64951-04-8
• Molecular Formula: C8H8N2O2S
• Molecular Weight: 196.23
• Mol File: 64951-04-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 87 °C
• Appearance: /
• Density: 1.42 g/cm³
• Refractive Index: 1.668
• CAS DataBase Reference: ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE(64951-04-8)
• EPA Substance Registry System: ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE(64951-04-8)

Safety Data

• Hazardous Substances Data: 64951-04-8(Hazardous Substances Data)

Usage

General Description

ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE is a chemical compound with the molecular formula C9H9N3O2S. It is an imidazole derivative with a carboxylate functional group attached to the 6th carbon atom of the thiazole ring. ETHYL IMIDAZO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE has potential applications in medicinal chemistry, as it can serve as a building block for the synthesis of various bioactive compounds. Its unique chemical structure gives it potential for use in drug development and as a starting material for the synthesis of pharmaceuticals and agrochemicals. It is important to handle and use this compound with care, following all safety guidelines and regulations, as it may pose hazards if not used properly.

InChI:InChI=1/C8H8N2O2S/c1-2-12-7(11)6-5-10-3-4-13-8(10)9-6/h3-5H,2H2,1H3

Upstream product

• 96-50-4 2-thiazolylamine 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 120107-62-2 imidazo<2,1-b>thiazole-6-carboxylic acid tosylhydrazide 
• 120107-61-1 6-formylimidazo<2,1-b>thiazole 
• 53572-98-8 imidazo[2,1-b]thiazole-6-carboxylic acid 

Relevant articles and documents

A new multifunctional sensor for sequential recognizing of Zn2+ and PPi in acetonitrile solution and detection of In3+ in DMF solution

A simple multifunctional sensor, X, was designed and synthesized based on 8-hydroxy-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-9-carbaldehyde and imidazo[2,1-b]thiazole, which could sequentially identify Zn2+ and PPi in acetonitrile buffer solution through the presence or absence of fluorescent signals and could detect In3+ in DMF buffer solution with obvious fluorescence enhancement. The detection limit for Zn2+, PPi and In3+ were calculated to be 4.58 × 10?8 M, 1.07 × 10?8 M and 2.9 × 10?8 M, respectively. Moreover, X could quantitatively detect Zn2+, PPi and In3+ in real water samples with the satisfactory recovery rate (90.1 %–97.6 %) and RSD (0.86 %–3.09 %). In addition, the complexation ratio between X and metal ions (Zn2+ and In3+) was 1:1, which was proved by mass spectrometry titration. The binding mode and sensing mechanism of X to metal ions (Zn2+ and In3+) were verified by Gaussian calculation based on B3LYP/6-31 G(d) and B3LYP/LanL2DZ basis set.

A simple sensor based on imidazo[2,1-b]thiazole for recognition and differentiation of Al3+, F? and PPi

Based on imidazo[2,1-b]thiazole and 2,3-dihydroxybenzaldehyde, a simple sensor, (E)-N'-(2,3-dihydroxybenzylidene)imidazo[2,1-b]thiazole-6-carbohydrazide (X), was designed and synthesized and its fluorescence responses to various ions were explored in DMF/

A simple fluorescent schiff base for sequential detection of Zn2+ and PPi based on imidazo[2,1-b]thiazole

A simple fluorescent schiff base, X, based on imidazo[2,1-b]thiazole-6-carboxylic acid and 3-ethoxy-2-hydroxybenzaldehyde, was designed and synthesized for detection of Zn2+ and PPi. X showed excellent sensitivity and selectivity toward Zn