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Uridine, 4-O-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)-, 5'-(2-cyano-1-phenylethyl carbonate) 3'-[2-(4-nitrophenyl)ethyl bis(1-methylethyl)phosphoramidite] is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

649759-89-7

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649759-89-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 649759-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,5 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 649759-89:
(8*6)+(7*4)+(6*9)+(5*7)+(4*5)+(3*9)+(2*8)+(1*9)=237
237 % 10 = 7
So 649759-89-7 is a valid CAS Registry Number.

649759-89-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-O4-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)uridine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite

1.2 Other means of identification

Product number -
Other names Carbonic acid 2-cyano-1-phenyl-ethyl ester (2R,3R,4R,5R)-3-{diisopropylamino-[2-(4-nitro-phenyl)-ethoxy]-phosphanyloxy}-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-5-{4-[2-(4-nitro-phenyl)-ethoxy]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-2-ylmethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:649759-89-7 SDS

649759-89-7Downstream Products

649759-89-7Relevant academic research and scientific papers

Nucleotides. Part LXXIII: Oligoribonucleotide synthesis with the (2-cyano-1-phenylethoxy)carbonyl (2c1peoc) group for the 5′-hydroxy protection

Muench, Ursula,Pfleiderer, Wolfgang

, p. 2546 - 2565 (2007/10/03)

The (2-cyano-1-phenylethoxy)carbonyl (2c1peoc) group was developed as a new base-labile protecting group for the 5′-OH function in solid-phase synthesis of oligoribonucleotides via the phosphoramidite approach. The half-lives of its β-elimination process by 0.1M DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) were determined to be 7-14s by HPLC investigations. The 2′-OH function was protected with the acid-labile tetrahydro-4-methoxy-2H-pyran-4-yl (thmp) group, while the 2-(4-nitrophenyl)ethyl (npe) and 2-(4-nitrophenyl)ethoxycarbonyl (npeoc) groups were used for the protection of the base and phosphate moieties. The syntheses of the monomeric building blocks, both phosphoramidites and nucleoside-functionalized supports, as well as the build-up of oligoribonucleotides by means of this approach are described.

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