6499-12-3

Basic information

• Product Name: {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid
• Synonyms: {[(4-methylpiperidin-1-yl)carbonothioyl]thio}acetic acid
• CAS NO: 6499-12-3
• Molecular Formula: C₉H₁₅NO₂S₂
• Molecular Weight: 233.3509
• Mol File: 6499-12-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 369.5°C at 760 mmHg
• Flash Point: 177.3°C
• Density: 1.284g/cm³
• Vapor Pressure: 1.79E-06mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid(6499-12-3)
• EPA Substance Registry System: {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid(6499-12-3)

Safety Data

• Hazardous Substances Data: 6499-12-3(Hazardous Substances Data)

Usage

General Description

The chemical compound {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid is a sulfur-containing organic compound with a carbothioyl group attached to a piperidine ring. Its molecular structure consists of a piperidine ring with a methyl group and a carbothioyl group attached to it, and a sulfur atom attached to an acetic acid moiety. {[(4-methylpiperidin-1-yl)carbothioyl]sulfanyl}acetic acid may have potential applications in medicinal chemistry, due to the presence of the piperidine ring which is commonly found in many pharmaceutical drugs. Additionally, the carbothioyl group and sulfur atom may contribute to its reactivity and biological activity. Further research is needed to fully understand the properties and potential uses of this chemical compound.

Upstream product

• 626-58-4 4-methylpiperidin 
• 75-15-0 carbon disulfide 
• 3926-62-3 sodium monochloroacetic acid 

Relevant articles and documents

Synthesis, characterization and biological evaluation of novel 1-N-substituted thiocarbomoyl-3-ferrocenyl-2-pyrazoline derivatives

Some novel 1-N-substituted thiocarbomoyl-3-ferrocenyl-2-pyrazoline derivatives were synthesized and evaluated for in vitro antiamoebic activity against HM1:IMSS strain of Entamoeba histolytica. The results showed that most of the compounds exhibited promising activity (IC50 values in the range of 0.050-1.683 μM) than the reference drug metronidazole (IC50 = 1.78 μM). Active compounds were further screened for cytotoxicity against human embryonic kidney-293 (HEK-293) normal cell lines to ensure their toxic effect and the results revealed that active compounds were least toxic in the concentration range of 2.5-50 μM for 48 h and 2.5-25 μM for 72 h. At 100 μM for 48 h and at 50 μM for 72 h only four compounds 2c, 2h, 2k and 2l showed maximum viability and least cytotoxicity, respectively, concluding that all the screened compounds were least cytotoxic against human embryonic kidney-293 (HEK-293) normal cell lines in the concentration range of 2.5-50 and 2.5-25 μM.

Synthesis and characterization of a new series of hydroxy pyrazolines

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one obtained by Claisen-Schmidt condensation of 2-acetyl thiophene with benzaldehyde was converted into 2,3-dibromo-3-phenyl-1-(thiophen-2-yl)propan-1-one, which on treatment with various thiosemicarbazides in the presence of triethylamine in absolute ethanol, yielded the corresponding hydroxy pyrazolines 3a-h. All the compounds were characterized by IR, 1H NMR, and 13C NMR spectra. Copyright Taylor & Francis Group, LLC.