64991-29-3Relevant academic research and scientific papers
PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS
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Page/Page column 19-20, (2020/03/23)
Provided are novel naphthalene diimide (NDI) compound of Formula 1. The compounds may exhibit colour change from substantially transparent to substantially black upon electrochemical or photochemical stimulus and may be useful in smart windows.
In Vivo Gold Complex Catalysis within Live Mice
Tsubokura, Kazuki,Vong, Kenward K. H.,Pradipta, Ambara R.,Ogura, Akihiro,Urano, Sayaka,Tahara, Tsuyoshi,Nozaki, Satoshi,Onoe, Hirotaka,Nakao, Yoichi,Sibgatullina, Regina,Kurbangalieva, Almira,Watanabe, Yasuyoshi,Tanaka, Katsunori
supporting information, p. 3579 - 3584 (2017/03/21)
Metal complex catalysis within biological systems is largely limited to cell and bacterial systems. In this work, a glycoalbumin–AuIII complex was designed and developed that enables organ-specific, localized propargyl ester amidation with nearby proteins within live mice. The targeted reactivity can be imaged through the use of Cy7.5- and TAMRA-linked propargyl ester based fluorescent probes. This targeting system could enable the exploitation of other metal catalysis strategies for biomedical and clinical applications.
Study of intramolecular aminolysis in peptides containing N-alkylamino acids at position 2
Ryakhovsky, Vladimir V.,Ivanov, Andrey S.
supporting information; experimental part, p. 7070 - 7076 (2012/08/29)
Many peptides and proteins, containing Nα-alkylamino acids (including proline) at the second position, are prone to intramolecular aminolysis (IA) with elimination of N-terminal dipeptide sequence as 2,5-diketopiperazines (DKP). We synthesized a series of short peptides, containing N-alkylamino acids at position 2, and studied their stability in the presence of acetic acid and amines. The presence of side chains in the second and the third amino acid residues and alkylation at Nα of the third amino acid residue slowed down IA. Nα-Alkyl residue in the first amino acid residue impeded IA only in peptides, containing three or more residues. Side chains of the first amino acids did not affect significantly the cleavage rates. Acetic acid promoted IA more strongly than aqueous ammonia, while tertiary amines were less effective. Peptides with methionine-S-oxide residues were more labile than the unoxidized analogs, suggesting intramolecular assistance of the S-oxide group in aminolysis. Surprisingly, intermediate compounds of the formula Boc-Met-MeXaa-Sar-NHR underwent rapid cleavage (endopeptolysis) upon attempted acidolytic deprotection.
Efficient microwave assisted syntheses of 2,5-diketopiperazines in aqueous media
Perez-Picaso, Lemuel,Escalante, Jaime,Olivo, Horacio F.,Rios, Maria Yolanda
experimental part, p. 2836 - 2849 (2009/12/06)
Aqueous in situ one-pot N-Boc-deprotection-cyclization of Nα-Boc-dipeptidyltert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields. This protocol is rapid, safe, environmentally friendly, and high
