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4-Hydroxypregn-4-ene-3,20-dione, also known as 4-hydroxyprogesterone, is a naturally occurring steroid hormone derived from the parent compound pregnane. It is a key intermediate in the biosynthesis of various hormones, including corticosteroids and sex hormones. This chemical plays a crucial role in the regulation of the body's stress response, immune function, and reproductive processes. The molecule features a pregnane core with a hydroxyl group at the 4-position and ketone groups at the 3 and 20 positions, which contribute to its biological activity and chemical reactivity. 4-Hydroxypregn-4-ene-3,20-dione is an important compound in the field of endocrinology and has been studied for its potential therapeutic applications in conditions related to hormonal imbalances.

650-66-8

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650-66-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 650-66-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 650-66:
(5*6)+(4*5)+(3*0)+(2*6)+(1*6)=68
68 % 10 = 8
So 650-66-8 is a valid CAS Registry Number.

650-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxyprogesterone

1.2 Other means of identification

Product number -
Other names (8S,9S,10R,13S,14S,17S)-17-Acetyl-4-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:650-66-8 SDS

650-66-8Relevant academic research and scientific papers

New Routes to 4-Substituted Steroids: Synthesis of 4-Cyanoprogesterone, a Potent Inhibitor of the Enzyme 5&α-Reductase

Haase-Held, Margret,Hatzis. Maria,Mann, John

, p. 2907 - 2912 (2007/10/02)

Two new synthetic route to 4-substituted derivatives of progesterone are described: one involves the palladium-catalysed addition of alkenes to 4-(trifluoromethanesulfonyloxy)progesterone, and the other involves the addition of the anion of acetonitrile t

The Synthesis of 4-Cyanoprogesterone: A Potent Inhibitor of the Enzyme 5-&α-Reductase

Haase-Held, Margret,Hatzis, Maria,Mann, John

, p. 2999 - 3000 (2007/10/02)

We describe a number of synthetic approaches to 4-cyanoprogresterone.This compound is a potent inhibitor, both in vitro and in vivo of the enzyme 5-alpha-reductase.

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