65006-97-5

Usage

Uses

Used in Pharmaceutical Industry:
Benzene, [(1-chlorocyclopropyl)sulfinyl]is used as an antibiotic for the treatment of tuberculosis and other infections caused by Mycobacterium tuberculosis. It is effective against drug-resistant strains of tuberculosis due to its potent bactericidal activity and ability to inhibit the synthesis of mycolic acids, which are essential components of the mycobacterial cell wall.

Upstream product

• 50337-59-2 cyclopropyl phenyl sulfoxide 
• 14633-54-6 cyclopropylphenylsulfide 

Downstream Products

• 7632-57-7 diphenylmethylenecyclopropene 
• 112033-50-8 N-cyclopropyl-N-methylphenylamine 
• 4170-69-8 isopropyl phenyl sulfoxide 
• 890534-61-9 N,N-diphenylaminocyclopropane 
• 208176-50-5 N-(4-chlorophenyl)-N-cyclopropylmethylamine 
• 1178527-60-0 C₁₄H₂₀ 
• 1178527-63-3 C₁₃H₁₈O 
• 1178527-62-2 C₁₃H₁₆O 
• 1178527-74-6 C₁₂H₁₆O 
• 1178527-77-9 C₁₅H₂₀O 
• 1178527-76-8 C₁₅H₁₈O 

Relevant academic research and scientific papers

A Straightforward Homologation of Carbon Dioxide with Magnesium Carbenoids en Route to α-Halocarboxylic Acids

The homologation of carbon dioxide with stable, (enantiopure) magnesium carbenoids constitutes a valuable method for preparing α-halo acid derivatives. The tactic features a high level of chemocontrol, thus enabling the synthesis of variously functionalized analogues. The flexibility to generate magnesium carbenoids through sulfoxide-, halogen- or proton- Mg exchange accounts for the wide scope of the reaction. (Figure presented.).

Reaction of magnesium cyclopropylidene with N-lithio arylamines: a method for generation of α-amino-substituted cyclopropylmagnesiums and a study for their reactivity with electrophiles

Magnesium cyclopropylidene was generated from 1-chlorocyclopropyl phenyl sulfoxide with i-PrMgCl in THF at -78 °C in high yield by a sulfoxide-magnesium exchange reaction. The generated magnesium cyclopropylidene was found to be reactive with N-lithio ary

A novel synthetic method for alkylidenecyclopropanes based on the reaction of magnesium cyclopropylidenes with lithium α-sulfonyl carbanions

Treatment of 1-chlorocyclopropyl phenyl sulfoxides with isopropylmagnesium chloride at low temperature gave magnesium cyclopropylidenes. The reaction of the generated carbenoids with lithium α-sulfonyl carbanions was found to afford alkylidenecyclopropane