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4-Quinazolinamine, N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[(4-methyl-2-morpholinyl)meth oxy]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

650581-40-1

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650581-40-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 650581-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,0,5,8 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 650581-40:
(8*6)+(7*5)+(6*0)+(5*5)+(4*8)+(3*1)+(2*4)+(1*0)=151
151 % 10 = 1
So 650581-40-1 is a valid CAS Registry Number.

650581-40-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:650581-40-1 SDS

650581-40-1Downstream Products

650581-40-1Relevant academic research and scientific papers

4-Substituted quinazoline derivatives as novel EphA2 receptor tyrosine kinase inhibitors

Lim, Chae Jo,Oh, Kwang-Seok,Ha, Jae Du,Lee, Jeong Hyun,Seo, Ho Won,Chae, Chong Hack,Kim, Dae-Ghon,Lee, Mi-Jin,Lee, Byung Ho

, p. 4080 - 4083 (2014/09/29)

Erythropoietin-producing hepatocellular receptor tyrosine kinase subtype A2 (EphA2) is an attractive therapeutic target for suppressing tumor progression. In our efforts to discover novel small molecules to inhibit EphA2, a class of compound based on 4-substituted quinazoline containing 7-(morpholin-2-ylmethoxy) group was identified as a novel hit by high throughput screening campaign. Structural modification of parent quinazoline scaffolds by introducing substituents on aniline displayed potent inhibitory activities toward EphA2.

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