651027-08-6 Usage
Uses
Used in Pharmaceutical Research:
5-Bromo-2,4-difluorobenzoic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemicals:
In the agrochemical industry, 5-Bromo-2,4-difluorobenzoic acid is used as a building block for the synthesis of various agrochemicals, such as pesticides and herbicides. Its reactivity and functional groups enable the creation of new compounds with improved efficacy and selectivity.
Used in Materials Science:
5-Bromo-2,4-difluorobenzoic acid is utilized in the development of advanced materials with specific properties, such as high thermal stability, chemical resistance, or optical properties. Its unique structure and functional groups contribute to the creation of novel materials with potential applications in various industries.
Used in Organic Synthesis:
As a versatile building block in organic chemistry, 5-Bromo-2,4-difluorobenzoic acid is used in the synthesis of a wide range of organic compounds. Its reactivity and functional groups allow for the formation of new molecules with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Overall, 5-Bromo-2,4-difluorobenzoic acid is a valuable compound with diverse applications across different industries, making it an essential component in the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 651027-08-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,1,0,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 651027-08:
(8*6)+(7*5)+(6*1)+(5*0)+(4*2)+(3*7)+(2*0)+(1*8)=126
126 % 10 = 6
So 651027-08-6 is a valid CAS Registry Number.
651027-08-6Relevant academic research and scientific papers
Exploring Structural Opportunities: The Regioflexible Substitution of 1,3-Difluorobenzene
Schlosser, Manfred,Heiss, Christophe
, p. 4618 - 4624 (2007/10/03)
To demonstrate the superiority of modern organometallic methods, the inexpensive starting material 1,3-difluorobenzene has been selectively converted into the three benzoic acids and all seven bromobenzoic acids containing the two fluorine atoms in homovicinal positions. The 2,6-difluorobenzoic acid (1) was prepared in a one-pot reaction consisting of direct metallation and carboxylation. The key step on the route to the bromobenzoic acid 4 was a deprotonation-triggered bromine migration from the 2- to the 4-position. All other products were attained through (2,6-difluorophenyl)triethylsilane (11). Consecutive deprotonation of the sites adjacent to the fluorine atoms, followed by appropriate electrophilic substitution, provided not only the acid 7 but also the dibromo and iodobromo derivatives 13 and 23. These in turn gave the isomers 14 and 24 upon base-mediated migration of the heaviest halogen, which made the acids 8 and 10 directly accessible. The regiocontrolled monodebromination of intermediate 14 afforded (4-bromo-2,6-difluoro)triethylsilane (15), which opened the route to the acids 3 and 5 (by carboxylation and protodesilylation) and to acid 9 (by carboxylation and bromodesilylation). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
