65103-50-6Relevant academic research and scientific papers
Ng-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the n g-substituent?
Igel, Patrick,Schneider, Erich,Schnell, David,Elz, Sigurd,Seifert, Roland,Buschauer, Armin
supporting information; experimental part, p. 2623 - 2627 (2010/03/24)
3-(1H-Imidazol-4-yl)propylguanidine (SK&F 91486, 4) was identified as a potent partial agonist at the human histamine H3 receptor (hH3R) and human histamine H4 receptor (hH4R). With the aim to increase selectivity for the
Synthesis and antinociceptive activity of orally active opioid peptides: Improvement of oral bioavailability by esterification
Ogawa, Tadashi,Araki, Mamoru,Miyamae, Tetsuhisa,Okayama, Toru,Hagiwara, Masaki,Sakurada, Shinobu,Morikawa, Tadanori
, p. 759 - 771 (2007/10/03)
To improve the oral bioavailability of a dermorphin tetrapeptide analog, Nα-1-iminoethyl-Tyr-D-MetO-Phe-MeβAla-OH (III), 1) which has a potent analgesic activity after oral administration, various derivatives were synthesized to incr
