651059-40-4

Upstream product

• 106773-36-8 4-methoxybenzyl-7-amino-3-chloromethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride 
• 134866-27-6 3-chloromethyl-7β-tert-butylcarbonylamino-3-cephem-4-carboxylic acid p-methoxybenzyl ester 
• 162095-92-3 4-methoxybenzyl 7β-t-butoxycarbonylamino-3-iodomethyl-3-cephemcarboxylate 
• 651059-35-7 C₁₆H₂₇NO₆ 
• 651059-34-6 (6R,7R)-3-((E)-(S)-3-Amino-4-hydroxy-but-1-enyl)-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-33-5 (6R,7R)-7-tert-Butoxycarbonylamino-3-{(E)-2-[(S)-2,2-dimethyl-3-(4-nitro-benzyloxycarbonyl)-oxazolidin-4-yl]-vinyl}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-36-8 (6R,7R)-3-[(E)-(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-hydroxy-but-1-enyl]-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 58177-82-5 (R)-tert-butyl 2-((R)-2-aminopropanamido)propanoate 
• 651059-37-9 (6R,7R)-3-[(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-hydroxy-butyl]-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Downstream Products

• 651059-41-5 (6R,7R)-3-{(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-3-[(R)-1-((R)-1-tert-butoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-propyl}-7-amino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant academic research and scientific papers

A Mechanism-Based Inhibitor Targeting the DD-Transpeptidase Activity of Bacterial Penicillin-Binding Proteins

Penicillin-binding proteins (PBPs) are responsible for the final stages of bacterial cell wall assembly. These enzymes are targets of β-lactam antibiotics. Two of the PBP activities include DD-transpeptidase and DD-carboxypeptidase activities, which carry