651059-33-5

Upstream product

• 651059-45-9 (R)-2,2-Dimethyl-oxazolidine-3,4-dicarboxylic acid 4-methyl ester 3-(4-nitro-benzyl) ester 
• 651059-44-8 N-(p-nitrobenzyloxycarbonyl)-D-serine methyl ester 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 162095-92-3 4-methoxybenzyl 7β-t-butoxycarbonylamino-3-iodomethyl-3-cephemcarboxylate 
• 134866-27-6 3-chloromethyl-7β-tert-butylcarbonylamino-3-cephem-4-carboxylic acid p-methoxybenzyl ester 
• 106773-36-8 4-methoxybenzyl-7-amino-3-chloromethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 651059-32-4 (R)-3-p-nitrobenzyloxycarbonyl-4-formyl-2,2-dimethyloxazolidine 

Downstream Products

• 651059-40-4 3-{3-(4-acetylamino-4-tert-butoxycarbonyl-butyrylamino)-3-[1-(1-tert-butoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-propyl}-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-41-5 (6R,7R)-3-{(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-3-[(R)-1-((R)-1-tert-butoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-propyl}-7-amino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-37-9 (6R,7R)-3-[(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-hydroxy-butyl]-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-36-8 (6R,7R)-3-[(E)-(S)-3-((R)-4-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-hydroxy-but-1-enyl]-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 651059-34-6 (6R,7R)-3-((E)-(S)-3-Amino-4-hydroxy-but-1-enyl)-7-tert-butoxycarbonylamino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant academic research and scientific papers

A Mechanism-Based Inhibitor Targeting the DD-Transpeptidase Activity of Bacterial Penicillin-Binding Proteins

Penicillin-binding proteins (PBPs) are responsible for the final stages of bacterial cell wall assembly. These enzymes are targets of β-lactam antibiotics. Two of the PBP activities include DD-transpeptidase and DD-carboxypeptidase activities, which carry