65117-26-2Relevant academic research and scientific papers
A general and efficient method for the selective synthesis of β-hydroxy sulfides and β-hydroxy sulfoxides catalyzed by gallium(III) triflate
Su, Weike,Chen, Jiuxi,Wu, Huayue,Jin, Can
, p. 4524 - 4527 (2008/02/05)
(Chemical Equation Presented) Gallium(III) triflate-catalyzed ring opening of epoxides affords β-hydroxy sulfides with high regioselectivity and chemoselectivity in high yields (84-97%) under solvent-free conditions. Additionally, a simple, efficient, and environmentally benign one-pot procedure for the synthesis of β-hydroxy sulfoxides in sole water has been developed for the first time. The process, promoted by a H2O 2-Ga(OTf)3 system, affords β-hydroxy sulfoxides in high yields (81-94%) and high chemoselectivity without any detectable overoxidation to β-hydroxy sulfones. The catalyst could be recovered easily after the reactions and reused without evident loss of activity.
ZnCl2 as an Efficient Catalyst in the Thiolysis of 1,2-Epoxides by Thiophenol in Aqueous Medium
Amantini, David,Fringuelli, Francesco,Pizzo, Ferdinando,Tortoioli, Simone,Vaccaro, Luigi
, p. 2292 - 2296 (2007/10/03)
ZnCl2 (5 mol%) is an efficient catalyst for the thiolysis of 1,2-epoxides by thiophenol in water at pH 4.0. A variety of β-hydroxy phenylsulfides were obtained in short reaction times and excellent yields. Starting from cyclohexene oxide (1), two one-pot multi-step procedures in sole water (thiolysis/oxidation with H2O2) have been realized, for the chemoselective synthesis of the corresponding β-hydroxysulfoxides 19 or for the related β-hydroxysulfone 20.
The preparation of β-hydroxysulfoxides
Gabbi, Cristina,Ghelfi, Franco,Grandi, Romano
, p. 2857 - 2863 (2007/10/03)
Oxidation of β-hydroxy thioethers with MnO2-aqu.35%/HCl in methanol gives β-hydroxy sulfoxides in high yields.
