65117-26-2

Basic information

• Product Name: 2-(phenylsulfinyl)cyclohexanol
• CAS NO: 65117-26-2
• Molecular Formula: C₁₂H₁₆O₂S
• Molecular Weight: 224.3192
• Mol File: 65117-26-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 417°C at 760 mmHg
• Flash Point: 206°C
• Density: 1.25g/cm³
• Vapor Pressure: 1.07E-07mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 2-(phenylsulfinyl)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylsulfinyl)cyclohexanol(65117-26-2)
• EPA Substance Registry System: 2-(phenylsulfinyl)cyclohexanol(65117-26-2)

Safety Data

• Hazardous Substances Data: 65117-26-2(Hazardous Substances Data)

Usage

Chemical class

Organosulfur compounds

Physical state

Colorless, oily liquid

Molecular weight

216.32 g/mol

Uses

Organic synthesis, pharmaceutical research, chiral catalysts, asymmetric synthesis

Medicinal properties

Anti-inflammatory, anti-cancer agent

Upstream product

• 108-98-5 thiophenol 
• 286-20-4 cyclohexane-1,2-epoxide 
• 14032-04-3 trans-2-phenylthiocyclohexanol 
• 110-83-8 cyclohexene 
• 14032-04-3 (1R*,2R*)-2-thiophenylcyclohexanol 

Downstream Products

• 14032-04-3 (1R*,2R*)-2-thiophenylcyclohexanol 

Relevant articles and documents

A general and efficient method for the selective synthesis of β-hydroxy sulfides and β-hydroxy sulfoxides catalyzed by gallium(III) triflate

(Chemical Equation Presented) Gallium(III) triflate-catalyzed ring opening of epoxides affords β-hydroxy sulfides with high regioselectivity and chemoselectivity in high yields (84-97%) under solvent-free conditions. Additionally, a simple, efficient, and environmentally benign one-pot procedure for the synthesis of β-hydroxy sulfoxides in sole water has been developed for the first time. The process, promoted by a H2O 2-Ga(OTf)3 system, affords β-hydroxy sulfoxides in high yields (81-94%) and high chemoselectivity without any detectable overoxidation to β-hydroxy sulfones. The catalyst could be recovered easily after the reactions and reused without evident loss of activity.

The preparation of β-hydroxysulfoxides

Oxidation of β-hydroxy thioethers with MnO2-aqu.35%/HCl in methanol gives β-hydroxy sulfoxides in high yields.

Sodium Bromite: A New Selective Reagent for the Oxidation of Sulfides and Alcohols

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