65147-82-2Relevant academic research and scientific papers
Reaction of Nitriles under Acidic Conditions. Part VI. Synthesis of Condensed 4-Chloro- and 4-Aminopyrimidines from ortho-Aminonitriles
Shishoo, C. J.,Devani, M. B.,Bhadti, V. S,Jain, K. S.,Ananthan, S.
, p. 119 - 126 (2007/10/02)
Condensation of a nitrile with benzene, furan and thiophene ortho-aminonitriles in the presence of dry hydrogen chloride yields condensed 4-chloropyrimidines, condensed 4-aminopyrimidines or a mixture of the two condensed pyrimidines in varying proportions depending upon the nature of the nitrile and the substrate, ortho-aminonitrile.
Reaction of Nitriles under Acidic Conditions. Part I. A General Method of Synthesis of Condensed Pyrimidines
Dave, K. G.,Shishoo, G. J.,Devani, M. B.,Kalyanaraman, R.,Ananthan, S.,et. al.
, p. 1497 - 1500 (2007/10/02)
Nitriles are known to give rise to salts of different compositions with halogen acids.Many of the reactions undergone by nitriles under the influence of halogen acids are, in many cases, assumed to proceed via the intermediate formation of highly reactive
