651749-64-3Relevant academic research and scientific papers
Synthesis of type II β-turn surrogate dipeptides based on syn-α-amino-α,β-dialkyl-β-lactams
Palomo, Claudio,Aizpurua, Jesus M.,Ganboa, Inaki,Benito, Ana,Cuerdo, Lourdes,Fratila, Raluca M.,Jimenez, Azucena,Loinaz, Iraida,Miranda, Jose I.,Pytlewska, Kinga R.,Micle, Andreea,Linden, Anthony
, p. 4443 - 4446 (2007/10/03)
(Chemical equation presented) The achiral bis(trimethylsilyl)methyl group acts as an efficient stereochemical determinant of the α-alkylation reaction in β-branched α-phenyloxazolidinyl- or α- diphenyloxazolidinyl-β-lactams and provides the first stereoco
Development of a New Family of Conformationally Restricted Peptides as Potent Nucleators of β-Turns. Design, Synthesis, Structure, and Biological Evaluation of β-Lactam Peptide Analogue of Melanostatin
Palomo, Claudio,Aizpurua, Jesus M.,Benito, Ana,Miranda, Jose Ignacio,Fratila, Raluca M.,Matute, Carlos,Domercq, Maria,Gago, Federico,Martin-Santamaria, Sonsoles,Linden, Anthony
, p. 16243 - 16260 (2007/10/03)
Novel enantiopure (i)-(β-lactam)-(Gly)-(i+3) peptide models, defined by the presence of a central α-alkyl-αamino-β-lactam ring placed as the (i+1) residue, have been synthesized in a totally stereocontrolled way by α-alkylation of suitable N-[bis(trimethy
