910097-79-9Relevant academic research and scientific papers
Functionalization of N-[(silyl)methyl]-β-lactam carbanions with carbon electrophiles
Palomo, Claudio,Aizpurua, Jesus M.,Benito, Ana,Cuerdo, Lourdes,Fratila, Raluca M.,Miranda, Jose I.,Linden, Anthony
, p. 6368 - 6373 (2006)
Latent acidity of α-alkyl-α-amino-N-[(silyl)methyl]-β- lactams enabled a concise entry to lithium nonenolate N-methyl-azetidinone carbanions lithiated α′ to the β-lactam nitrogen, owing to the stabilizing "α-effect" of one or two trimethylsilyl groups. s
