65273-68-9Relevant academic research and scientific papers
Well-Defined Phosphine-Free Iron-Catalyzed N-Ethylation and N-Methylation of Amines with Ethanol and Methanol
Lator, Alexis,Gaillard, Sylvain,Poater, Albert,Renaud, Jean-Luc
, p. 5985 - 5990 (2018)
An iron(0) complex bearing a cyclopentadienone ligand catalyzed N-methylation and N-ethylation of aryl and aliphatic amines with methanol or ethanol in mild and basic conditions through a hydrogen autotransfer borrowing process is reported. A broad range of aromatic and aliphatic amines underwent mono- or dimethylation in high yields. DFT calculations suggest molecular hydrogen acts not only as a reducing agent but also as an additive to displace thermodynamic equilibria.
Preparation and biological actions of some symmetrically N,N-disubstituted dopamines.
Cannon et al.
, p. 248,252 (2007/10/06)
The title compounds have been synthesized and evaluated for emetic effects in the dog, actions on the cardioaccelerator nerve in the cat, pecking in pigeons, and for behavioral effects following both peripheral and direct intracerebral injection into the
