65309-15-1Relevant academic research and scientific papers
The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide y Y2 receptor
Swanson, Devin M.,Wong, Victoria D.,Jablonowski, Jill A.,Shah, Chandra,Rudolph, Dale A.,Dvorak, Curt A.,Seierstad, Mark,Dvorak, Lisa K.,Morton, Kirsten,Nepomuceno, Diane,Atack, John R.,Bonaventure, Pascal,Lovenberg, Timothy W.,Carruthers, Nicholas I.
scheme or table, p. 5552 - 5556 (2011/10/12)
A series of small molecules based on a chemotype identified from our compound collection were synthesized and tested for binding affinity (IC 50) at the human Neuropeptide Y Y2 receptor (NPY Y 2). Six of the 23 analogs tes
PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR
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Page/Page column 41, (2009/03/07)
The present invention is directed to piperazinyl derivatives useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of said compounds for the treatment and / or prevention of disorders, diseases and conditions mediated by the NPY Y2 receptor.
