65311-06-0

Basic information

• Product Name: [2-[Benzyl(carboxymethyl)amino]ethylimino]diacetic acid
• Synonyms: [2-[Benzyl(carboxymethyl)amino]ethylimino]diacetic acid;N-[2-[Bis(carboxymethyl)amino]ethyl]-N-benzylglycine;Glycine, N-[2-[bis(carboxyMethyl)aMino]ethyl]-N-(phenylMethyl)-
• CAS NO: 65311-06-0
• Molecular Formula: C₁₅H₂₀N₂O₆
• Molecular Weight: 324.33
• Mol File: 65311-06-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [2-[Benzyl(carboxymethyl)amino]ethylimino]diacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [2-[Benzyl(carboxymethyl)amino]ethylimino]diacetic acid(65311-06-0)
• EPA Substance Registry System: [2-[Benzyl(carboxymethyl)amino]ethylimino]diacetic acid(65311-06-0)

Safety Data

• Hazardous Substances Data: 65311-06-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 4152-09-4 N-benzylethylenediamine 
• 193143-30-5 di-tert-butyl 2,2'-((2-(benzyl(2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)diacetate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 186349-54-2 di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)diacetate 

Relevant articles and documents

RuIII complexes of edta and dtpa polyaminocarboxylate analogues and their use as nitric oxide scavengers

In this study a series of RuIII complexes, chelated by analogues of ethylenediaminetetraacetic acid (edta) and diethylenetriaminepentaacetic acid (dtpa), were produced and tested for NO scavenging ability. Modifications to the edta and dtpa ligand frameworks were made in an effort to alter the reactivity, aqueous stability and pharmacokinetics of the resulting Ru III complexes. The X-ray structure of the nitrosyl complex 38 confirms that the RuIII complex 27 reacts with NO to form a linear {Ru-NO}[6] complex. The nitrosyl complex [C15H 15N4O11Ru] crystallized in the P21/c space group with a = 12.731(3) A, b = 10.894(2) A, c = 14.241 (3) A, β= 107.320(4)°, V = 1885.6(7) A3, and Z = 4. Kinetic studies on the reactions of 14 (k = 2.38 × 106 M -1 s-1) and 27 (k = 2.30 × 105 M -1 s-1) with NO exemplify the difference in chemical properties obtained by ligand framework manipulation. Binding constants of 14 (KB = 5×106 M-1) and 27 (KB = 2 × 105 M-1) with NO were also measured, indicating the tight binding of NO by the RuIII complexes. The activity of the RuIII complexes to scavenge nitric oxide was evaluated using RAW264 murine macrophage cells. Ligand analogues of edta that have a pyridine donor as part of the N,N chelate such as 20 and 24 exhibit similar scavenging activity to the parent compound. Ligand analogues of dtpa that have R groups at the central amine in place of the carboxylic acid such as 31, 34, and 37 are also efficient NO scavengers. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.

Hydroformylation of olefins using azoxy-dentated ligands

At a temperature in the range 100° C to 225° C the destructive dissociation of cobalt carbonyl compounds to cobalt metal and residue is inhibited by the action of one or more azoxy-dentated chelation ligands.