65359-73-1Relevant academic research and scientific papers
Synthesis of Allenyl Esters by Horner-Wadsworth-Emmons Reactions of Ketenes Mediated by Isopropylmagnesium Bromide
Sano, Shigeki,Matsumoto, Tomoya,Yano, Teppei,Toguchi, Munehisa,Nakao, Michiyasu
, p. 2135 - 2138 (2015/09/15)
The synthesis of conjugated allenyl esters (tri-substituted allenes) was achieved by magnesium(II)-mediated Horner-Wadsworth-Emmons reaction of methyl bis(2,2,2-trifluoroethyl)phosphonoacetate with disubstituted ketenes. In addition, a novel access to α-fluorinated allenyl carboxamides (tetrasubstituted allenes) is presented.
Bifunctionalized allenes. Part VIII. An efficient and varied method for the synthesis of 2-sulfonylated alka-2,3-dienoates
Ivanov, Ivaylo K.,Christov, Valerij Ch.
supporting information, p. 913 - 919 (2013/08/23)
An efficient and varied method for the synthesis of 2-sulfonylated alka-2,3-dienoates by intermediate formation of allenecarboxylates, allenyl sulfones, and propargyl sulfinates using the relatively high acidity of the hydrogen atom at the allenic C-1 ato
Enantioselective nickel-catalyzed cross-coupling reactions of trialkynylindium reagents with racemic secondary benzyl bromides
Caeiro, Jorge,Sestelo, Jose Perez,Sarandeses, Luis A.
, p. 741 - 746 (2008/12/22)
The first enantioselective sp-sp3 cross-coupling reaction between alkynyl organometals and racemic benzyl bromides is reported. The coupling is performed at room temperature by using NiBr2.diglyme and (S)-(/Pr)-Pybox as the catalytic
Iron porphyrin-catalyzed olefination of ketenes with diazoacetate for the enantioselective synthesis of allenes
Li, Chuan-Ying,Wang, Xiao-Bing,Sun, Xiu-Li,Tang, Yong,Zheng, Jun-Cheng,Xu, Zheng-Hu,Zhou, Yong-Gui,Dai, Li-Xin
, p. 1494 - 1495 (2007/10/03)
In the presence of Ph3P and catalytic Fe(TCP)Cl, ketenes could react with EDA to give allenes in high yields under neutral conditions for the first time. By employing chiral phosphine instead of PPh3, allenes could be synthesized with high enantioselectivity (93-98% ee) in good yields. Copyright
Olefination of ketenes for the enantioselective synthesis of allenes via an ylide route
Li, Chuan-Ying,Zhu, Ben-Hu,Ye, Long-Wu,Jing, Qing,Sun, Xiu-Li,Tang, Yong,Shen, Qi
, p. 8046 - 8053 (2008/02/08)
Pseudo-C2-symmetric chiral phosphorus ylide is designed and synthesized for the enantioselective preparation of allenic esters, amides, ketone, and nitrile. Up to 92% ee is achieved.
