654056-82-3

Basic information

• Product Name: N-BOC-4-broMo-3-Methylaniline
• Synonyms: N-BOC-4-broMo-3-Methylaniline;(4-Bromo-3-methyl-phenyl)-carbamic acid tert-butyl ester
• CAS NO: 654056-82-3
• Molecular Formula: C12H16BrNO2
• Molecular Weight: 286.16494
• Mol File: 654056-82-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 297.3±33.0 °C(Predicted)
• Appearance: /
• Density: 1.356±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.99±0.70(Predicted)
• CAS DataBase Reference: N-BOC-4-broMo-3-Methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-4-broMo-3-Methylaniline(654056-82-3)
• EPA Substance Registry System: N-BOC-4-broMo-3-Methylaniline(654056-82-3)

Safety Data

• Hazardous Substances Data: 654056-82-3(Hazardous Substances Data)

Upstream product

• 1591-97-5 4-bromo-3-methylphenyl isocyanate 
• 75-65-0 tert-butyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 6933-10-4 amino-5-bromo-2-toluene 

Downstream Products

• 929890-98-2 4'-tert-butoxycarbonylamino-2'-methyl-biphenyl-3-carboxylic acid 

Relevant articles and documents

Thiamine hydrochloride as a recyclable organocatalyst for the efficient and chemoselective N-tert-butyloxycarbonylation of amines

Thiamin hydrochloride promoted highly efficient and ecofriendly approach has been described for the chemoselective N-tert-butyloxycarbonylation of amines under solvent-free conditions at ambient temperature. The demonstrated approach has been applicable for the N-Boc protection of variety of aliphatic, aryl, heteroaryl amines. The chemoselective protection of amino group occurs in chiral amines and amino alcohol without racemization in high yield. Thiamin hydrochloride is stable, economical, easy to handle and environmentally friendly.

Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates

N-Boc- and N-Cbz-protected amines are directly converted into amides by a novel rhodium-catalyzed coupling of arylboroxines and carbamates, replacing the traditional two-step deprotection-condensation sequence. Both protected anilines and aliphatic amines are efficiently transformed into a wide variety of secondary benzamides, including sterically hindered and electron-deficient amides, as well as in the presence of acid-labile and reducible functional groups.

ELECTROACTIVE MATERIALS

There is disclosed a compound having Formula I or Formula I': In Formula I and Formula I': Ar1 and Ar2 are the same or different and are aryl groups; R1 through R5 are independently the same or different at each occurrence and are D, F, alkyl groups, aryl groups, alkoxy groups, silyl groups, or crosslinkable groups; R6 is H, D, or halogen; a through e are independently an integer from 0 to 4; f is 1 or 2; g is 0, 1 or 2; h is 1 or 2; and n is an integer greater than 0.