65417-74-5

Upstream product

• 120-57-0 piperonal 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 

Downstream Products

• 888316-54-9 methyl (1'R,4'S)-2-(4'-benzoyloxy-2'-cyclohexen-1'-yl)-2-N-[6''-bromo-3'',4''-(methylene-dioxy)benzyl]carbamoylacetate 
• 6871-58-5 (+)-γ-lycorane 
• 18034-03-2 nornitidine 
• 226570-99-6 N-(6-bromo-3,4-dimethoxybenzyl)-N-(cyclohex-1-enyl)-2,2,2-trichloroacetamide 
• 63814-03-9 1,2,3,3a,4,5,12b,12c-octahydro-7H-1,3-benzodioxolo[5,6-c]pyrrolo[3,2,1-ij]quinoline 
• 67496-29-1 1-bromo-6-aminomethyl-3,4-(methylenedioxy)-benzene 

Relevant academic research and scientific papers

Palladium-Catalyzed α-Arylation of Silylenol Ethers in the Synthesis of Isoquinolines and Phenanthridines

A diverse array of isoquinolines and phenanthridines have been accessed by developing a two-step, one-pot method constituting regioselective palladium-catalyzed Kuwajima-Urabe α-arylation of silylenol ethers and acid-mediated deprotection, annulation, and aromatization. Structural diversity in the silylenol ethers leads to three different classes of isoquinolines and phenanthridines from which related natural products can be derived. The synthetic utility of this method by the quick assembly of the natural product trispheridine is also demonstrated.

Rapid and convergent assembly of natural benzo[c]phenanthridines by palladium/norbornene catalysis

A straightforward total synthesis of a small panel of natural benzo[c]phenanthridines is described. The selective coupling of an aryl triflate with a bromobenzylamine by means of palladium/norbornene joint catalysis and a sequential transfer hydrogenation

Catalytic asymmetric transformations with fine-tunable biphenol-based monodentate ligands

A library of new fine-tunable monodentate phosphite and phosphoramidite ligands based on chiral biphenol have been designed and developed. These monodentate phosphorus ligands have exhibited excellent enantioselectivity in the Pd-catalyzed asymmetric allylic alkylation and Rh-catalyzed asymmetric hydrogenation.