65418-75-9

Usage

InChI:InChI=1/C17H14O2/c1-13-3-8-15(9-4-13)17(18)12-7-14-5-10-16(19-2)11-6-14/h3-6,8-11H,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 5395-43-7 tri(p-tolyl)antimony 
• 624-31-7 4-tolyl iodide 
• 768-60-5 4-methoxyphenylacetylen 
• 874-60-2 4-methyl-benzoyl chloride 
• 696-62-8 para-iodoanisole 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 
• 104-87-0 4-methyl-benzaldehyde 
• 99-94-5 p-Toluic acid 

Downstream Products

• 1358811-60-5 ethyl 5-(4-methoxyphenyl)-3-(p-tolyl)thiophene-2-carboxylate 
• 65205-51-8 3-(4′-methoxyphenyl)-5-(4″-methylphenyl)isoxazole 

Relevant academic research and scientific papers

Synthesis and Characterization of Ag@g?C3N4 and Its Photocatalytic Evolution in Visible Light Driven Synthesis Of Ynone

The primary aim of this work is to synthesize photocatalyst to promote the synthesis of ynones. In this context, we synthesized AgNPs@g?C3N4 nanocomposite. The nanocomposite was characterized by using SEM, HR-TEM, XRD, EDS, ICP-AES,

N-heterocyclic carbene palladium complex crystal and synthetic method thereof and application of n-heterocyclic carbene palladium complex crystal in preparation of alpha,beta-unsaturated ketone compounds

The invention discloses an n-heterocyclic carbene palladium complex crystal and a synthetic method thereof and application of the n-heterocyclic carbene palladium complex crystal in preparation of alpha,beta-unsaturated ketone compounds. A structural form

Synthesis of Water-Soluble Blue-Emissive Tricyclic 2-Aminopyridinium Salts by Three-Component Coupling-(3+3)-Anellation

The (3+3) anellation of alkynones and cyclic amidines is a novel and unexpected approach to generate intensively blue luminescent tricyclic 2-aminopyridinium salts with quantum yields Φf up to 63 % in water. By implementation into a consecutive three-component reaction, these title compounds are obtained rapidly and efficiently in a diversity-oriented fashion. Most interestingly, these bi- and tricyclic 2-aminopyridinium salts emit in dichloromethane and water solutions, thus making them interesting novel luminophore probes for bioanalytics, as well as in the solid state, thus making them blue emitters with tunable efficiency.

Solvent free synthesis of ynones using magnetically recoverable Copper-ferrite nanoparticles

A general and efficient biogenic CuFe2O4 MNP's catalyzed synthesis of ynones has been reported for the first time. The reaction occurs in solvent free conditions without the use of any harsh conditions. The average diameter of the na

Rapid access to unsymmetrical tolanes and alkynones by sequentially palladium-catalyzed one-pot processes

Alkynones as well as unsymmetrically substituted tolanes (diarylalkynes) can be rapidly generated in a one-pot fashion via sequential palladium catalysis. Terminal alkynes, formed in situ by protecting-group free palladium-catalyzed coupling of aryl iodides with ethynyl magnesium bromide, are subsequently transformed by Sonogashira coupling with aryl halides or aroyl chlorides to furnish unsymmetrically substituted alkynes in good to excellent yields.

A highly efficient heterogeneous palladium-catalyzed cascade three-component reaction of acid chlorides, terminal alkynes and hydrazines leading to pyrazoles

In the presence of 0.5 mol% of 3-(2-aminoethylamino)propyl-functionalized MCM-41-immobilized palladium(II) complex [MCM-41-2N-Pd(OAc)2] and 1.0 mol% of CuI, acid chlorides were coupled with terminal alkynes in Et3N at 50 °C to give α,β-unsaturated ynones, which were converted in situ into pyrazoles by the cycloaddition of hydrazines at room temperature with acetonitrile as cosolvent. The cascade reactions generated a variety of pyrazole derivatives in moderate to good yields, and this heterogeneous palladium catalyst exhibited higher catalytic activity than PdCl2(PPh3)2 and could be recovered and reused for at least 10 consecutive trials without any decreases in activity.

Carboxylic acid [...]end alkyne couplingacetylenic ketone the method of preparation

The invention discloses a method for preparing acetyenic ketone by coupling carboxylate triazinyl ester with terminal alkyne. According to the method, palladium acetate is taken as a catalyst, and a carboxylate triazinyl ester compound is taken as an elec

Dual-immobilized copper catalyst: Carbon nitride-supported copper nanoparticles catalyzed oxidation of propargylic alcohols

Copper nanoparticles were supported and modified by carbon nitride, which was utilized as support and might work as a kind of immobilized N-donor ligand. The modified nanoparticle catalyst was evaluated with the oxidation of propargylic alcohols and showed highly catalytic efficiency as well as significant ligand or support effect in the reaction. The dual-immobilized nanoparticle catalyst could be recycled for 3 times at least without an obvious decrease in catalytic activities.

Privilege Ynone Synthesis via Palladium-Catalyzed Alkynylation of "Super-Active Esters"

A neat palladium-catalyzed alkynylation reaction was developed with "super-active ester" as the carbonyl electrophile, which provides a clean and efficient synthetic protocol for a broad array of ynone compounds under CO-, Cu-, ligand-, and base-free conditions. The superior activity of triazine ester was rationalized by the strong electron-withdrawing ability and the unique affinity of triazine on palladium. A mechanistic experiment clearly demonstrated that the N-Pd coordination of triazine plays a crucial role for the highly efficient C-O activation. (Chemical Equation presented).

Preparation of 3,5-disubstituted pyrazoles and isoxazoles from terminal alkynes, aldehydes, hydrazines, and hydroxylamine

The reaction of terminal alkynes with n-BuLi, and then with aldehydes, followed by the treatment with molecular iodine, and subsequently hydrazines or hydroxylamine provided the corresponding 3,5-disubstituted pyrazoles or isoxazoles in good yields with high regioselectivity, through the formations of propargyl secondary alkoxides and α-alkynyl ketones. The present reactions are one-pot preparation of 3,5-disubstituted pyrazoles from terminal alkynes, aldehydes, molecular iodine, and hydrazines, and 3,5-disubstituted isoxazoles from terminal alkynes, aldehydes, molecular iodine, and hydroxylamine.