654673-34-4 Usage
Uses
Used in Pharmaceutical Industry:
2',4'-DIFLUORO-3-(4-FLUOROPHENYL)PROPIOPHENONE is used as a chemical intermediate for the synthesis of pharmaceutical compounds, leveraging its unique structure to contribute to the development of new drugs and medicinal agents.
Used in Chemical Research and Development:
In the realm of chemical research, 2',4'-DIFLUORO-3-(4-FLUOROPHENYL)PROPIOPHENONE serves as a key component in the creation and testing of novel materials and chemical entities, potentially leading to advancements in various chemical applications.
Used in Organic Synthesis:
2',4'-DIFLUORO-3-(4-FLUOROPHENYL)PROPIOPHENONE is utilized as a building block in organic synthesis, where its fluorinated and aromatic structure can be further modified to produce a variety of organic compounds for diverse uses.
Check Digit Verification of cas no
The CAS Registry Mumber 654673-34-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,4,6,7 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 654673-34:
(8*6)+(7*5)+(6*4)+(5*6)+(4*7)+(3*3)+(2*3)+(1*4)=184
184 % 10 = 4
So 654673-34-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H11F3O/c16-11-4-1-10(2-5-11)3-8-15(19)13-7-6-12(17)9-14(13)18/h1-2,4-7,9H,3,8H2
654673-34-4Relevant academic research and scientific papers
CHEMICAL COMPOUNDS
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Page 88, (2010/02/06)
Compounds of formula (I):wherein variable groups are as defined within; for use in the inhibition of 11betaHSD1 are described
Azole compounds designed by molecular modelling show antifungal activity as predicted
Karki, Rajeshri G.,Gokhale, Vijay M.,Kharkar, Prashant S.,Kulkarni, Vithal M.
, p. 372 - 381 (2007/10/03)
Rational approaches involving drug discovery technologies such as computational and combinatorial chemistry and high throughput screening have been useful tools to design and discover new drugs more efficiently. The interplay among structure-activity relationships, computer modelling, chemical synthesis and pharmacological testing can lead to better products for a particular therapeutic purpose. The work presented in this paper reports an example of successful application of computer-aided drug design method to find new azole antifungal agents. The designed compounds have been synthesized in the laboratory and tested for antifungal activity against Candida albicans ATCC 24433 in vitro. Two compounds exhibit good activity in vitro, which can be optimized for better activity.
