65481-69-8

Basic information

• Product Name: 2-AMINONORBORNANE HYDROCHLORIDE
• Synonyms: 2-NORBORNANAMINE HYDROCHLORIDE;2-AMINONORBORNANE HYDROCHLORIDE;(+/-)-ENDO-2-NORBORNYLAMINE HYDROCHLORIDE;(+/-)-ENDO-BICYCLO[2.2.1]HEPT-2-YLAMINE HYDROCHLORIDE;endo-bicyclo[2.2.1]heptan-2-amine hydrochloride;ENDO-2-AMINONORBORNANE HYDROCHLORIDE);endo-Aminonorbornane hydrochloride;Einecs 265-790-3
• CAS NO: 65481-69-8
• Molecular Formula: C₇H₁₃N*ClH
• Molecular Weight: 147.65
• EINECS: 265-790-3
• Mol File: 65481-69-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 295 °C (dec.)(lit.)
• Boiling Point: 203.4°C at 760 mmHg
• Flash Point: 76.8°C
• Appearance: /
• Vapor Pressure: 0.233mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-AMINONORBORNANE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINONORBORNANE HYDROCHLORIDE(65481-69-8)
• EPA Substance Registry System: 2-AMINONORBORNANE HYDROCHLORIDE(65481-69-8)

Safety Data

• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 65481-69-8(Hazardous Substances Data)

Usage

General Description

2-Aminonorbornane hydrochloride is a chemical compound with the molecular formula C7H13N·HCl. It is a white to off-white crystalline solid that is commonly used as a reagent in organic synthesis. 2-AMINONORBORNANE HYDROCHLORIDE is used as a chiral auxiliary in the preparation of enantiomerically pure compounds and as a resolving agent for racemic mixtures. It is also used as a building block in the synthesis of pharmaceuticals and agrochemicals. 2-Aminonorbornane hydrochloride is a versatile chemical with a wide range of applications in the fields of medicine, agriculture, and material science.

InChI:InChI=1/C7H13N.ClH/c8-7-4-5-1-2-6(7)3-5;/h5-7H,1-4,8H2;1H/t5-,6+,7-;/m1./s1

Upstream product

• 4576-48-1 bicyclo[2.2.1]heptan-2-one oxime 
• 497-38-1 2-norbornanone 
• 934-28-1 bicyclo(2.2.1)heptane-2-endo-carboxylic acid 
• 498-66-8 norborn-2-ene 
• 85231-79-4 diethyl N-exo-norbornylphosphoramidate 
• 934-29-2 acide bicyclo<2.2.1>heptane carboxylique-2 exo 

Downstream Products

• 822-98-0 (1RS,4SR)-norcamphane-2-amine 
• 111013-45-7 5-exo-acetoxy-2-endo-benzoylamino norbornane 
• 105512-48-9 N-((1R,2R,4R,5S)-5-Hydroxy-bicyclo[2.2.1]hept-2-yl)-benzamide 
• 24374-32-1 2-endo-benzoylamino norbornane 
• 128413-89-8 N-(1S,2R,4R)-Bicyclo[2.2.1]hept-2-yl-N'-(2-iodo-phenyl)-guanidine 
• 128413-88-7 N-(exo-norborn-2-yl)-N'-(2-iodophenyl)guanidine 
• 6343-65-3 endo-2-nitronorbornane 
• 128413-91-2 N-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl-N'-o-tolyl-guanidine 
• 5024-97-5 endo-2-Dimethylamino-norbornan 

Relevant articles and documents

Potential Synthetic Adaptogens: V. Synthesis of Cage Monoamines by the Schwenk–Papa Reaction

The reduction of cage ketoximes under Schwenk–Papa reaction conditions was studied to establish that the d,l, d- and l-camphor oximes are smoothly reduced to the corresponding amines in high yields. At the same time, d,l-norcamphor and adamantan-2-one oximes undergo partial catalytic deoximation to form a mixture of the corresponding amines and alcohols.

Alkylwanderungen bei Sextettumlagerungen

The migration aptitude of alkyl groups in the Beckmann-, the Criegee-, and the isonitrile-nitrile rearrangements were investigated.The relative rearrangement rates of substituted benzyl groups are an expression of the charge on the migrating carbon at transition state.From the relative rates of migration of exo- and endo-2-norbornyl groups the geometrical changes at the migrating carbon is estimated.Finally, the different influence of α-branching in the migrating group is discussed for these and some other rearrangements.