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• 462-06-6 fluorobenzene 
• 403-43-0 4-fluorobenzoyl chloride 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 401-55-8 ethyl bromofluoroacetate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 352-34-1 4-fluoro-1-iodobenzene 

Relevant academic research and scientific papers

Nickel-Catalyzed Coupling Reaction of α-Bromo-α-fluoroketones with Arylboronic Acids toward the Synthesis of α-Fluoroketones

A nickel-catalyzed coupling reaction of α-bromo-α-fluoroketones with arylboronic acids was reported, which provides an efficient pathway to access 2-fluoro-1,2-diarylethanones in high yields. We also disclosed the synthesis of the monofluorination agents

A synthesis method of [...] acetone derivatives

The invention provides a method for synthesizing [...] acetone derivatives, characterized in that includes: formula (IV) is shown in the compounds are dissolved in 1, 4 - dioxane (dioxane) in, adding catalyst trifluoromethanesulfonic acid nickel (II) (Ni

Method for synthesizing monofluorobromoacetone derivative by applying Grignard reagent

The invention provides a method for synthesizing a monofluorobromoacetone derivative by applying a Grignard reagent. The method is characterized by comprising the steps that ethyl monofluorobromoacetate is dissolved into anhydrous THF, replacing is conducted 3-4 times with nitrogen, the Grignard reagent is dropwise added at -78-0 DEG C for a reaction, and the monofluorobromoacetone derivative is obtained after treatment; the structural formula of the ethyl monofluorobromoacetate is the formula (I), the structural formula of the Grignard reagent is the formula (II), the structural formula of the monofluorobromoacetone derivative is the formula (III), and the formulas are defined in the description, wherein R1 is phenyl or naphthalene or substituted phenyl or alkyl or heterocyclic, and the substituent in the substituted phenyl is selected from one or multiple of hydrogen, fluorine, bromine, chlorine, trifluoromethoxy, methoxy, methyl and phenyl. The method has the advantages of being high in yield, short in reaction time, simple in preparation method, convenient, efficient, easy to implement, suitable for industrial production and capable of being applied to the fields of medicine, pesticide and the like.

α,α-Alkylation-Halogenation and Dihalogenation of Sulfoxonium Ylides. A Direct Preparation of Geminal Difunctionalized Ketones

A one-pot alkylation–halogenation of ketosulfoxonium ylides in the presence of alkyl halides is described. The method furnishes several gem-difunctionalized haloketones (an alkyl and F, Cl, Br, or I) in good yields. Replacing alkyl halides with a mixture of electrophilic halogen species and various halide anions led to gem-dihalogenated ketones containing a combination of the same or two different halogens. Kinetic isotopic effects as well as reaction kinetic experiments give insight to the mechanism of these reactions.

OXIME DERIVATIVE, METHOD OF PRODUCING THE SAME AND INSECTICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT

PROBLEM TO BE SOLVED: To provide a compound having excellent insecticidal effect and useful as an active ingredient of an insecticide. SOLUTION: This invention provides an oxime derivative represented by general formula (1) (where Ra, X and n represent definitions described in the specifications) and an insecticide that comprises the same as an active ingredient. COPYRIGHT: (C)2015,JPOandINPIT