65527-62-0 Usage
Uses
Used in Pharmaceutical Research:
N-Ethylnorlysergic Acid N,N-diethylaMide is used as a research compound in the pharmaceutical industry for studying its potential hallucinogenic effects and exploring its applications in therapeutic settings. Its structural similarity to LSD allows researchers to investigate its interactions with the serotonin receptors in the brain, which may provide insights into the development of novel treatments for various mental health disorders.
Used in Forensic Analysis:
In the forensic science industry, N-Ethylnorlysergic Acid N,N-diethylaMide is used as a reference material for the identification and analysis of designer drugs and new psychoactive substances (NPS). Its presence in seized drug samples can be detected and confirmed using various analytical techniques, such as mass spectrometry and chromatography, to aid in the enforcement of drug regulations and the prosecution of drug-related crimes.
Check Digit Verification of cas no
The CAS Registry Mumber 65527-62-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,2 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 65527-62:
(7*6)+(6*5)+(5*5)+(4*2)+(3*7)+(2*6)+(1*2)=140
140 % 10 = 0
So 65527-62-0 is a valid CAS Registry Number.
65527-62-0Relevant academic research and scientific papers
Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives
Hoffman,Nichols
, p. 1252 - 1255 (2007/10/02)
A convenient method for the synthesis of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives was developed. A series of these compounds was synthesized and tested for substitution in the two-lever drug discrimination assay, in rats trained to discriminate injections of d-LSD tartrate (185.5 nmol/kg, ip) from saline. A dose-response curve for each of the compounds in the series was generated. Structure-activity relationships were developed, based on comparison of the estimated ED50 values from these curves. Of the compounds that substituted for LSD, the N(6)-ethyl and -allyl were approximately 2-3 times more potent than LSD itself. The N(6)-propyl was equipotent to LSD, while the isopropyl derivative was half as active. The n-butyl compound was 1 order of magnitude less potent than LSD, suggesting a similarity to the SAR of certain serotonin and dopamine agonists. By contrast, no generalization occurred to norlysergic acid N,N-diethylamide and the N(6)-2-phenethyl derivative.
