6555-29-9

Usage

InChI:InChI=1/C12H16O3/c1-9(8-12(13)15-3)10-4-6-11(14-2)7-5-10/h4-7,9H,8H2,1-3H3

Upstream product

• 142060-21-7 methyl 3-(4'-methoxyphenyl)but-2-enoate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 7428-99-1 2-(4-methoxyphenyl)propan-2-ol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 623-43-8 crotonic acid methyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 6555-30-2 3-(4-methoxyphenyl)butyric acid 

Relevant academic research and scientific papers

Palladium-Catalyzed Carbonylation of sec- and tert-Alcohols

A general palladium-catalyzed synthesis of linear esters directly from sec- and tert-alcohols is described. Compared to the classic Koch–Haaf reaction, which leads to branched products, this new transformation gives the corresponding linear esters in high yields and selectivity. Key for this protocol is the use of an advanced palladium catalyst system with L2 (pytbpx) as the ligand. A variety of aliphatic and benzylic alcohols can be directly used and the catalyst efficiency for the benchmark reaction is outstanding (turnover number up to 89 000).

ANTI-HCMV COMPOSITIONS AND METHODS

This document relates to compounds useful as agents for preventing or treating human cytomegalovirus (HCMV) infections.

Rhodium-catalyzed heck-type coupling of boronic acids with activated alkenes in an aqueous emulsion

Intermolecular couplings between arylboronic acids and activated alkenes catalyzed by a water-soluble tert-bulyl amphosrhodium complex were found to progress at room temperature and generated Heck-type products with high yields and excellent selectivity. Substitution on the alkene component encouraged the formation of products arising from a conjugate addition-protonation process. In the case of Heck product formation, it was necessary to add two equivalents of the alkene component whereby one equivalent is believed to act as a sacrificial hydride acceptor.

Studies on the Liverwort Sesquiterpene Alcohol Tamariscol. Synthesis and Absolute Configuration

The relative configuration of the liverwort sesquiterpene alcohol (-)-tamariscol 1 has been confirmed by total synthesis and the absolute configuration has been established from the CD spectrum of the hydrindanone degradation product from (-)-1.