65619-94-5

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 65619-92-3 8-(dimethylamino)-1,4-dioxaspiro-[4.5]-decane-8-carbonitrile 
• 591-20-8 3-Bromophenol 
• 80165-54-4 Dimethyl-{8-[3-(tetrahydro-pyran-2-yloxy)-phenyl]-1,4-dioxa-spiro[4.5]dec-8-yl}-amine 
• 57999-49-2 3-(tetrahydropyran-2-yloxy)phenyl bromide 

Downstream Products

• 65619-95-6 4-(meta-hydroxyphenyl)-4-dimethylaminocyclohexanone 
• 76626-22-7 3-(1-Dimethylamino-4-hydroxy-4-methyl-cyclohexyl)-phenol 
• 76626-23-8 3-(1-Dimethylamino-4-hydroxy-4-methyl-cyclohexyl)-phenol 
• 76626-21-6 3-(1-Dimethylamino-4-hydroxy-cyclohexyl)-phenol 
• 70895-12-4 3-{4-[2-(4-Chloro-phenyl)-ethyl]-1-dimethylamino-4-hydroxy-cyclohexyl}-phenol 
• 70895-11-3 3-{4-[2-(4-Chloro-phenyl)-ethyl]-1-dimethylamino-4-hydroxy-cyclohexyl}-phenol 
• 70895-08-8 3-(1-Dimethylamino-4-hydroxy-4-phenethyl-cyclohexyl)-phenol 
• 70895-07-7 3-(1-Dimethylamino-4-hydroxy-4-phenethyl-cyclohexyl)-phenol 
• 76626-24-9 3-(4-Benzyl-1-dimethylamino-4-hydroxy-cyclohexyl)-phenol 
• 70895-09-9 3-(4-Benzyl-1-dimethylamino-4-hydroxy-cyclohexyl)-phenol 

Relevant academic research and scientific papers

4-Amino-4-phenylcyclohexanone ketal compositions and process of use

A class of new 4-amino-4-arylcyclohexanones, their ketals, and acid addition salts have been synthesized and found to be useful for relieving pain in animals. Their analgesic activity appears to be of high order, and in addition some exhibit narcotic antagonist activity that is useful in modifying the cardiovascular, respiratory, and behavioral depression caused by other analgesics. Several show mixed analgesic and narcotic antagonist activity. Preferred compounds of the class are 4-(m-hydroxyphenyl)-4-dimethylaminocyclohexanone ethylene ketal, and 4-(m-hydroxyphenyl)-4-(n-butylmethylamino)cyclohexanone ethylene ketal as free bases and as their hydrochloride salts. Processes for synthesis and intermediates are described. Unit dosage forms and therapeutic treatments are disclosed.