656256-40-5Relevant academic research and scientific papers
Preorganized bis-zinc phosphodiester cleavage catalysts possessing natural ligands: A lesson pertinent to bimetallic artificial enzymes
Worm, Karen,Chu, Feiya,Matsumoto, Kazunari,Best, Michael D.,Lynch, Vincent,Anslyn, Eric V.
, p. 741 - 747 (2007/10/03)
Two preorganized bis-zinc receptors (2 and 3) were synthesized wherein the metals were ligated with ligands present in natural phosphodiesterases: imidazoles and carboxylates. The intrametallic distance is near 45 A, that found in natural nucleases and ot
