65659-15-6

Basic information

• Product Name: Phosphoric acid, ethyl methyl phenyl ester
• CAS NO: 65659-15-6
• Molecular Formula: C9H13O4P
• Molecular Weight: 216.174
• Mol File: 65659-15-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phosphoric acid, ethyl methyl phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid, ethyl methyl phenyl ester(65659-15-6)
• EPA Substance Registry System: Phosphoric acid, ethyl methyl phenyl ester(65659-15-6)

Safety Data

• Hazardous Substances Data: 65659-15-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 46207-73-2 ethyl phenyl hydrogen phosphate 
• 59288-82-3 phosphoric acid methyl ester-phenyl ester; tetramethylammonium salt 
• 13781-15-2 (+/-)-ethyl methyl chlorophosphate 
• 108-95-2 phenol 
• 1021-47-2 ethyl methyl p-nitrophenyl phosphate 
• 100-67-4 potassium phenolate 

Relevant articles and documents

Method for preparing organophosphate compound from P(O)-OH-containing compound and alcohol through efficient esterification

The invention provides a method for efficiently and highly selectively synthesizing an organophosphate derivative containing different substitute functional groups. The method is characterized by adopting a polypeptide catalyst as a condensation reagent, taking a P(O)-OH-containing compound and alcohol as reaction substrates, and adding an organic solvent in a reaction system. The method disclosed by the invention has the advantages that the catalyst is cheap in cost and easy to obtain; the substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of an obtained target product is close to 100 percent, and the yield is up to 90 percent or more. According to the method provided by the invention, the defects of a traditional method for synthesizing an organophosphate compound that the reaction selectivity is poor, the reaction steps are tedious, the yield is low, reagents which are harmful to the environment are required to be used, and the like are solved, and a good industrial application prospect is obtained. Meanwhile, the invention also provides the corresponding organophosphate derivative containing different substitute functional groups.

Selective phosphorylation process

A one step process for the preparation of phosphate esters of phenol comprising reacting phenol with a dimethyl disulfide and a trialkyl phosphite.