65699-23-2

Upstream product

• 50330-59-1 8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide 
• 65698-99-9 N,N-dimethyl 2-amino-2-(2-(2-chlorobenzoyl)-5-chlorophenylazo)acetamide 
• 65698-98-8 C₁₇H₁₅Cl₂N₃O₃ 
• 85815-52-7 N,N-dimethyl 2-chloro-2-(2-(2-chlorobenzoyl)-5-chlorophenylazo)acetoacetamide 
• 65699-21-0 2',5-dichloro-2-(3-dimethylcarbamoyl-5-benzyloxycarbonylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 2958-36-3 (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone 
• 5123-55-7 Nα-phthaloyl-L-phenylalanine 

Downstream Products

• 65699-25-4 2',5-dichloro-2-(3-dimethylcarbamoyl-5-L-phenylalanylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 

Relevant academic research and scientific papers

Synthesis and biological activity of (3,5-disubstituted-1H-1,2,4-triazol-1-yl)benzophenone derivatives (1)

The synthesis of (5-acylaminomethyl-3-carbamoyl-1H-1,2,4-triazol-1-yl)benzophenone derivatives is described. Acylation of the key intermediate, 1-benzoylphenylazo-1-aminoacetamide followed by cyclization in the presence of acid afforded 1H-1,2,4-triazole derivates. These compounds were evaluated for their central nervous system (CNS) activity. Some of these compounds exhibited high activities in anti-pentylene tetrazole and rotarod test in mice orally administered.