85815-52-7

Upstream product

• 5810-11-7 2-chloro-N,N-dimethylacetoacetamide 
• 2958-36-3 (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone 

Downstream Products

• 65698-99-9 N,N-dimethyl 2-amino-2-(2-(2-chlorobenzoyl)-5-chlorophenylazo)acetamide 
• 65699-00-5 2',5-dichloro-2-(3-dimethylcarbamoyl-5-phthalylglycylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-21-0 2',5-dichloro-2-(3-dimethylcarbamoyl-5-benzyloxycarbonylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-31-2 1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-[(2-pyrrolidin-1-yl-acetylamino)-methyl]-1H-[1,2,4]triazole-3-carboxylic acid dimethylamide 
• 65699-28-7 5-(benzoylamino-methyl)-1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-1H-[1,2,4]triazole-3-carboxylic acid dimethylamide 
• 65699-32-3 1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-{[(N-methyl-glycyl)-amino]-methyl}-1H-[1,2,4]triazole-3-carboxylic acid dimethylamide 
• 65720-27-6 2',5-dichloro-2-(3-dimethylcarbamoyl-5-dimethylaminoacetylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-27-6 2',5-dichloro-2-(3-dimethylcarbamoyl-5-chloroacetylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 99593-25-6 2',5-dichloro-2-(3-dimethylcarbamoyl-5-glycylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-29-8 1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-(isobutyrylamino-methyl)-1H-[1,2,4]triazole-3-carboxylic acid dimethylamide 
• 65699-30-1 5-(acetylamino-methyl)-1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-1H-[1,2,4]triazole-3-carboxylic acid dimethylamide 
• 65699-25-4 2',5-dichloro-2-(3-dimethylcarbamoyl-5-L-phenylalanylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-24-3 2',5-dichloro-2-(3-dimethylcarbamoyl-5-L-leucylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 
• 65699-23-2 2',5-dichloro-2-(3-dimethylcarbamoyl-5-phthalylphenylalanylaminomethyl-1H-1,2,4-triazol-1-yl)benzophenone 

Relevant academic research and scientific papers

Synthesis and biological activity of (3,5-disubstituted-1H-1,2,4-triazol-1-yl)benzophenone derivatives (1)

The synthesis of (5-acylaminomethyl-3-carbamoyl-1H-1,2,4-triazol-1-yl)benzophenone derivatives is described. Acylation of the key intermediate, 1-benzoylphenylazo-1-aminoacetamide followed by cyclization in the presence of acid afforded 1H-1,2,4-triazole derivates. These compounds were evaluated for their central nervous system (CNS) activity. Some of these compounds exhibited high activities in anti-pentylene tetrazole and rotarod test in mice orally administered.