657389-99-6

Basic information

• Product Name: 4-(Bromomethyl)-2-methyl-1,3-oxazole
• Synonyms: 4-(Bromomethyl)-2-methyl-1,3-oxazole;4-(BROMOMETHYL)-2-METHYLOXAZOLE
• CAS NO: 657389-99-6
• Molecular Formula: C₅H₆BrNO
• Molecular Weight: 176.012
• Mol File: 657389-99-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(Bromomethyl)-2-methyl-1,3-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Bromomethyl)-2-methyl-1,3-oxazole(657389-99-6)
• EPA Substance Registry System: 4-(Bromomethyl)-2-methyl-1,3-oxazole(657389-99-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 657389-99-6(Hazardous Substances Data)

Usage

General Description

4-(Bromomethyl)-2-methyl-1,3-oxazole is a chemical compound with the molecular formula C6H6BrNO. It is a white to light yellow solid that is used in organic synthesis as a building block for various pharmaceutical and agrochemical products. 4-(Bromomethyl)-2-methyl-1,3-oxazole is a brominated derivative of 2-methyl-1,3-oxazole and contains a bromomethyl group, which makes it useful for introducing functional groups onto the oxazole ring. It is a versatile intermediate in the production of diverse chemical compounds and has applications in the development of new drugs and other fine chemicals. However, it is important to handle this compound with care, as it is a brominated compound and can be hazardous if not properly controlled and used.

Upstream product

• 155884-28-9 4,5-dihydro-2-methyl-oxazole-4-carboxylic acid methyl ester 
• 141567-53-5 4-hydroxymethyl-2-methyloxazole 
• 85806-67-3 2-methyl-oxazole-4-carboxylic acid methyl ester 

Downstream Products

• 552850-11-0 C₅₅H₉₀BrNO₁₁Si₂ 
• 552850-01-8 C₅₃H₈₄BrNO₁₀Si₂ 
• 552850-00-7 6-[9-bromo-1-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-3-methyl-nona-2,4,8-trienyl]-2-(4-{2-[6-(2,2-dimethoxy-ethyl)-4-(4-methoxy-benzyloxy)-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazol-2-ylmethyl)-4-methoxy-tetrahydro-pyran-2-ol 
• 552849-99-7 4-{(E)-2-[(2R,3R,4S,5S,6R)-6-(2,2-Dimethoxy-ethyl)-4-(4-methoxy-benzyloxy)-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-2-methyl-oxazole 

Relevant articles and documents

AZIRIDINE CONTAINING EPOTHILONE ANALOGS, METHODS OF SYNTHESIS, METHODS OF TREATMENT, AND DRUG CONJUGATES

In one aspect, the present disclosure provides epothilone analogs of the formula: (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided.

SUBSTITUTED OXOPYRIDINE DERIVATIVES

The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

PYRROLE ANTIFUNGAL AGENTS

The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof; wherein: R1, R2, R3, R4, R5, R6, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.