657427-16-2

Upstream product

• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 111-42-2 2,2'-iminobis[ethanol] 

Downstream Products

• 455890-94-5 N,N-bis(2-chloroethyl)-2-nitrobenzenesulfonamide 
• 290326-06-6 3,6,9-tris-(2-nitro-benzenesulfonyl)-3,6,9,15-tetraaza-bicyclo[9.3.1]pentadeca-1⁽¹⁴⁾,11⁽¹⁵⁾,12-triene 
• 657423-45-5 N,N-bis-(2-trifluoromethanesulfonyloxyethyl)-2-nitrobenzenesulfonamide 
• 1026799-45-0 N,N-bis-(2-trifluoromethanesulfonyl-ethyl)-2-nitrobenzenesulfonamide 

Relevant academic research and scientific papers

Method for preparing 1,4,7,10-tetraaza-2,6-pyridinophane

The invention relates to a novel method for preparing 1,4,7,10-tetraaza-2,6-pyridinophane. 2,6-dimethylamino pyridine serving as a raw material is subjected to amino protection through o-/p-nitrobenzenesulfonyl and reacts with N,N-di(2-chloroethyl)-o-/p-n

Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatme

Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.

NEW COMPOUNDS

The present invention relates to new compounds of formula (I), wherein P, Q, X1, X2, X3, X4, R, R1, R2, R3, R4, R5, R6, R7, m, n, o, p and q are defined as in any one of claims 1 to 12, a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.