6575-11-7

Usage

Uses

Used in Chemical Synthesis:
2-Amino-6-chlorobenzonitrile is used as a reagent for the preparation of oxo pentylcyclopentyl acetamide derivatives, which are essential in the development of plant growth regulators. Its unique chemical structure allows for specific reactions and modifications that contribute to the synthesis of these biologically active compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Amino-6-chlorobenzonitrile may be utilized as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Its chemical properties make it a versatile building block for creating molecules with specific therapeutic properties.
Used in Agrochemical Industry:
2-Amino-6-chlorobenzonitrile also finds application in the agrochemical industry, particularly in the development of plant growth regulators. These regulators play a crucial role in enhancing crop yield, quality, and resistance to various environmental stresses.

InChI:InChI=1/C7H5ClN2/c8-6-2-1-3-7(10)5(6)4-9/h1-3H,10H2

Upstream product

• 6575-07-1 2-chloro-6-nitrobenzonitrile 

Downstream Products

• 77326-28-4 N-(3-Chloro-2-cyano-phenyl)-oxalamic acid ethyl ester 
• 873-32-5 2-Chlorobenzonitrile 
• 3475-97-6 2-chloro-6-sulfamoyl-benzoic acid, methyl ester 
• 80563-88-8 methyl 6-chloro-2-chlorosulfonyl-benzoate 
• 120257-00-3 2-chloro-6-isocyanatosulfonyl-benzoic acid methyl ester 
• 666261-56-9 2-(3-chloro-2-cyano-phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid (tetrahydropyran-4-ylmethyl)-amide 
• 20895-91-4 1-(2-amino-6-chloro-phenyl)-ethanone 
• 934474-82-5 3-chloro-2-(1H-tetrazol-5-yl)aniline 
• 934474-82-5 3-chloro-2-(2H-tetrazol-5-yl)-phenylamine 
• 606145-80-6 N-(3-chloro-2-cyanophenyl)benzonitrile 
• 33265-72-4 1-(2-aminomethylphenyl)-1H-pyrroloe hydrochloride 
• 1420627-35-5 (S)-2-(1-aminoethyl)-5-chloro-3-phenylquinazoline-4(3H)-one 
• 35490-90-5 2-amino-6-chlorobenzaldehyde 
• 39885-08-0 (2-amino-6-chlorophenyl)methanol 

Relevant academic research and scientific papers

Highly selective transfer hydrogenation of functionalised nitroarenes using cobalt-based nanocatalysts

Anilines are important feedstock for the synthesis of a variety of chemicals such as dyes, pigments, pharmaceuticals and agrochemicals. The chemoselective catalytic reduction of nitro compounds represents the most important and prevalent process for the manufacture of functionalized anilines. Consequently, the development of selective catalysts for the reduction of nitro compounds in the presence of other reducible groups is a major challenge and is crucial. In this regard, herein we show that the cobalt oxide (Co3O4-NGr@C) based nano-materials, prepared by the pyrolysis of cobalt-phenanthroline complexes on carbon constitute highly selective catalysts for the transfer hydrogenation of nitroarenes to anilines using formic acid as a hydrogen source. Applying these catalysts, a series of structurally diverse and functionalized nitroarenes have been reduced to anilines with unprecedented chemo-selectivity tolerating halides, olefins, aldehyde, ketone, ester, amide and nitrile functionalities.

N-(Aminophenyl)oxamic Acids and Esters as Potent, Orally Active Antiallergy Agents

A series of N-(2-cyano-substituted-phenyl)oxamates was prepared by acylation of the appropriate anthranilonitrile with ethyloxalyl chloride.Hydrolysis with sodium hydroxide gave the corresponding oxamic acid sodium salts.These compounds were extremely potent when tested in the rat passive cutaneous anaphylaxis (PCA assay either by the ip or the po route of administration).One of the sodium salts, oxoacetic acid sodium salt (11a, Wy-41 195), has ED50 value of 0.07 mg/kg po and has been selected for further evaluation.