19407-57-9

Basic information

• Product Name: 4(1H)-Quinazolinone, 5-chloro-2-phenyl-
• CAS NO: 19407-57-9
• Molecular Formula: C14H9ClN2O
• Molecular Weight: 256.691
• Mol File: 19407-57-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 5-chloro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 5-chloro-2-phenyl-(19407-57-9)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 5-chloro-2-phenyl-(19407-57-9)

Safety Data

• Hazardous Substances Data: 19407-57-9(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 54166-95-9 2-amino-6-chlorobenzamide 
• 144-62-7 oxalic acid 
• 107485-64-3 2-chloro-6-nitro-benzoic acid amide 
• 100-51-6 benzyl alcohol 
• 6575-11-7 2-amino-6-chlorobenzonitrile 
• 100-52-7 benzaldehyde 
• 609-65-4 o-chlorobenzoyl chloride 
• 444112-59-8 2-chloro-N-(quinolin-8-yl)benzamide 
• 1670-14-0 benzamidine monohydrochloride 
• 6575-07-1 2-chloro-6-nitrobenzonitrile 
• 2835-06-5 phenylglycin 

Relevant articles and documents

Palladium-catalyzed one-pot synthesis of 2-substituted quinazolin-4(3H)-ones fromo-nitrobenzamide and alcohols

Palladium-catalyzed 2-substituted quinazolin-4(3H)-one formation from readily availableo-nitrobenzamides and alcohols using hydrogen transfer is described. Various quinazolin-4(3H)-ones were obtained in good to high yields. The cascade reaction including

Polystyrene-Supported Palladium (Pd?PS)-Catalyzed Carbonylative Annulation of Aryl Iodides Using Oxalic Acid as a Sustainable CO Source for the Synthesis of 2-Aryl Quinazolinones

An efficient and convenient strategy for the synthesis of diversely substituted quinazolinones from o-carbamoyl/cyano aniline and aryl iodides using oxalic acid as a CO source under polystyrene supported palladium (Pd?PS) nanoparticles (NPs) catalyzed con

Chemoselective Trifluoroethylation Reactions of Quinazolinones and Identification of Photostability

Herein, we report chemoselective trifluoroethylation routes of unmasked 2-arylquinazolin-4(3H)-ones using mesityl(2,2,2-trifluoroethyl)iodonium triflate at room temperature. Homologous C-, O-, and N-functionalized subclasses are accessed in a straightforward manner with a wide substrate scope. These chemoselective branching events are driven by Pd-catalyzed ortho-selective C-H activation at the pendant aryl ring and base-promoted reactivity modulation of the amide group, leveraging the intrinsic directing capability and competing pronucleophilicity of the quinazolin-4(3H)-one framework. Furthermore, outstanding photostability of the quinazolin-4(3H)-one family associated with nonradiative decay is presented.