658052-50-7

Upstream product

• 291758-11-7 1,4-anhydro-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-ribitol 
• 100-07-2 4-methoxy-benzoyl chloride 
• 66-22-8 uracil 
• 658052-48-3 1,4-anhydro-2-O-(p-methoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-ribitol 

Downstream Products

• 6741-73-7 1-(4-thio-β-D-ribofuransoyl)uracil 
• 1053628-67-3 4-Methoxy-benzoic acid (2R,3R,4S,5R)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-thiophen-3-yl ester 

Relevant academic research and scientific papers

A novel method for the synthesis of 4'-thiopyrimidine nucleosides using hypervalent iodine compounds.

The coupling reactions of cyclic sulfides with a silylated pyrimidine nucleobase using a hypervalent iodine reagent were investigated. The reaction of silylated uracil with cyclic sulfide 12 using PhI=O gave the desired beta-anomer 14 in moderate yield. 4