6583-41-1Relevant academic research and scientific papers
Synthesis of thiadiazolo-s-triazines for their antiviral activity based on QSAR studies
Pandey,Tusi,Tandon,Joshi,Bajpai
, p. 2583 - 2588 (2007/10/03)
2-Amino-5-aralkyl-1,3,4-thiadiazole 1 on treatment with benzaldehyde yields 5-aralkyl-2-benzylideno-imino-1,3,4-thiadiazole 2 which on reaction with ammonium thiocyanate cyclises to give 2-phenyl-7-aralkyl-1,3,4-thiadiazolo-[3,2-a]-s-triazine-5-[6H,7H]-thione 3. Reaction of 3 with p-toluene sulphonyl chloride in anhydrous chloroform gives 2-phenyl-3-(p-toluenesulphonyl)-7-aralkyl-1,3,4-thiadiazolo-[3, 2-al-s-triazine-5-[6H,7H]-thiones 4g-I. Benzoyl chloride also reacts with 3 in anhydrous pyridine giving 2-phenyl-3-(benzoyl)-7-aralkyl-1,3,4-thiadiazolo-[3,2-a]-s-triazine-5-[6H,7H] -thiones 4a-f in quantitative yields. The antiviral activities of 4 based on QSAR studies have been reported using physicochemical method.
Studies on the synthesis and bioactivity of some thiadiazole derivatives
Padhy, Arun Kumar,Nag,Panda
, p. 998 - 1001 (2007/10/03)
Several 2-aryl-3-(4-aryl-1,3,4-thiadiazolyl)-4-thiazolidinones 3 and several other fused heterocycles 5 have been prepared. Most of the compounds 3 have been screened for their fungicidal activity against two fungi Aspergillus clavatus and Aspergillus fum
Synthesis of Some Azomethine Derivatives of 2-Amino-5-phenyl-1,3,4-thiadiazole
Eremin,Golovanov,Krutikov,Lavrent'ev
, p. 138 - 140 (2007/10/03)
Azomethines derived from 2-amino-5-phenyl-1,3,4-thiadiazole were prepared by fusion of the starling amine with corresponding carhonyl compound. The method ensures yields of target products up to 97%. The composition and structure of the products were conf
Electronic Spectra and Acidity Constants of Hetero-Aromatic Schiff Bases Derived from 2-Amino-5-phenyl-1,3,4-Thiodiazole and Various Aromatic Aldehydes
Mahmoud, M. R.,Hamide, R. Abdel,Goad, F. Abdel
, p. 551 - 560 (2007/10/02)
The different absorption bands observed in the UV and visible electronic spectra of some arylidene 2-amino-1,3,4-thiodiazole are assigned to the possible electronic transitions.This is made in the light of investigating the spectra of the compounds in pur
Electronic Spectra and Acidity Constants of Schiff Bases Derived from 2-Amino-5-phenyl-1,3,4-thiadiazole and Various Aromatic Aldehydes
Mahmoud, M. R.,Abdel Hamide, R.,Abdel Goad, F.
, p. 144 - 148 (2007/10/02)
The different absorption bands observed in the UV and visible electronic spectra of some arylidene-2-amino-1,3,4-thiadiazoles in pure and mixed organic solvents of various polarities as well as in buffer solutions have been assigned.The possibility of the
