65840-96-2

Upstream product

• 16635-13-5 2'-hydroxy-4-methoxy-5'-methylchalcone 
• 1032-84-4 (E)-1-(2-hydroxy-5-methylphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 

Downstream Products

• 107095-31-8 1-Acetyl-3-(2-acetoxy-5-methylphenyl)-5-anisyl-Δ²-pyrazoline 
• 107095-28-3 1-Acetyl-5-anisyl-3-(2-hydroxy-5-methylphenyl)-Δ²-pyrazoline 

Relevant academic research and scientific papers

Synthesis of pyrazoline and isoxazoline in triethanolamine medium

Reactions of chalcones 1a-u with phenylhydrazine and hydrazine hydrate give pyrazolines 2a-u and with hydroxylamine hydrochloride yield isoxazolines 3a-c in triethanolamine medium. The structures of products are established by melting points, chemical studies and spectral data (IR and 1HNMR).

Synthesis of Isomeric Δ2-Pyrazolines

2'-Hydroxychalkones (I) react with hydrazine hydrate in ethanol to give 5-aryl-3-(2-hydroxyphenyl)-Δ2-pyrazolines (II) while in acetic acid the corresponding 5-aryl-1-acetyl-3-(2-hydroxyphenyl)-Δ2-pyrazolines (III) are obtained contr