65865-28-3

Usage

Uses

Used in Pharmaceutical Synthesis:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is used as a building block for the synthesis of pharmaceuticals, leveraging its furanyl and trifluoromethyl groups to introduce these functional groups into target molecules, which can enhance the pharmacological properties of the resulting compounds.
Used in Agrochemical Production:
In the agrochemical industry, [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is utilized as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used as a Solvent in Organic Synthesis:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL serves as a solvent in organic synthesis, facilitating a range of chemical reactions due to its unique properties as a colorless liquid at room temperature.
Used in the Production of Other Organic Compounds:
As an intermediate, [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is used in the production of other organic compounds, expanding its applications across various chemical industries.
Used in Biological Research:
[5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL is studied for its potential biological activities, particularly as an anti-inflammatory and anti-cancer agent, indicating its possible use in the development of new therapeutic agents.
However, due to the limited understanding of its toxicological properties, caution is advised when handling and using [5-(TRIFLUOROMETHYL)-2-FURYL]METHANOL to ensure safety in research and industrial applications.

Upstream product

• 56286-73-8 5-(trifluoromethyl)furan-2-carboxylic acid 

Downstream Products

• 17515-80-9 5-trifluoromethyl-2-furancarboxaldehyde 
• 1421458-34-5 C₃₀H₂₂F₃N₅O₅ 
• 1421458-57-2 C₃₁H₂₄F₃N₅O₅ 
• 1415359-43-1 C₁₆H₁₁F₄N₃O₃ 
• 56286-73-8 5-(trifluoromethyl)furan-2-carboxylic acid 
• 65865-25-0 5-(trifluoromethyl)furan-2-carbonyl chloride 
• 1421455-10-8 C₂₃H₂₀F₃N₅O₄ 
• 1421455-11-9 C₂₄H₂₂F₃N₅O₄ 
• 1421455-12-0 C₂₄H₂₂F₃N₅O₄ 
• 1421455-14-2 C₂₃H₂₂F₃N₅O₂ 
• 1421455-15-3 C₂₄H₂₄F₃N₅O₂ 
• 1421455-16-4 C₂₄H₂₄F₃N₅O₂ 
• 1415359-54-4 C₃₁H₂₄F₃N₅O₅ 
• 1415359-55-5 C₃₂H₂₆F₃N₅O₅ 

Relevant academic research and scientific papers

HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME

Disclosed are compounds of formula (I): or a pharmaceutically acceptable salt thereof; wherein Y, Ra, Ra', Rc, Rf, X2, Rd, Rd', Re, Re', m, and G have the values described herein and stereochemical configurations depicted at asterisked positions indicate absolute stereochemistry, useful as inhibitors of Sumo Activating Enzyme (SAE). Further provided are pharmaceutical compositions comprising a compound of the disclosure and methods of using the compositions in the treatment of proliferative, inflammatory, cardiovascular and neurodegenerative diseases or disorders.

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.