65958-18-1

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 589-92-4 1-methylcyclohexan-4-one 
• 91-59-8 naphthalen-2-ylamine 
• 591-24-2 3-Methylcyclohexanone 
• 68871-11-4 (3,4-dimethoxyphenyl)-methylene-2-naphthylamine 

Downstream Products

• 1258441-09-6 4-(3,4-dimethoxybenzyl)-1,4-dihydro-3H-spiro[benzo[f]quinoline-2,1'-cyclohexane]2',6'-dione 
• 901992-10-7 4-(3,4-dimethoxybenzyl)-4',4'dimethyl-1,4-dihydro-3H-spiro[benzo[f]quinoline-2,1'-cyclohexane]2',6'-dione 

Relevant academic research and scientific papers

Reaction of methylcyclohexanones with substituted benzaldehydes and 2-naphthylamine

Cascade heterocyclization of 3(4)-methylcyclohexanone, substituted benzaldehyde, and 2-naphthyl-amine in a polar solvent in the presence of hydrochloric acid afforded the corresponding 5-aryl-2(3)-methyl-1,2,3,4- tetrahydrobenzo[a]phenanthridines and 12-aryl-9(10)-methyl-8,9,10,11- tetrahydrobenz[a]acridines.

Condensation of 2-naphthylamine or N-benzyl-2-naphthylamines with formaldehyde and methyl 2,2-dimethyl-4,6-dioxocyclohexane-3-carboxylate

Condensation of 2-naphthylamine with formaldehyde and methyl 2,2-dimethyl-4,6-dioxocyclohexanecarboxylate afforded depending on the reaction conditions methyl 9,9-dimethyl-11-oxo-8,9,10,12-tetrahydro-7H-benzo[a]acridine- 10-carboxylate or 4-alkoxymethyl-1

Condensation of N-monosubstituted 2-naphthylamines, formaldehyde, and cyclic β-diketones. One-pot synthesis of 2,4-disubstituted derivatives of 1,2,3,4-tetrahydrobenzo[f]quinoline

Various spirocyclic derivatives of 1,2,3,4-tetrahydrobenzo[f]quinoline containing substituents in the positions 2 and 4 of the ring were obtained by one-pot multicomponent condensation of available N-benzyl-2-naphthylamines, formaldehyde, and cyclic β-dik