65961-86-6

Basic information

• Product Name: (3,4-dimethoxyphenyl)(oxo)acetonitrile
• CAS NO: 65961-86-6
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.1834
• Mol File: 65961-86-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 312.2°C at 760 mmHg
• Flash Point: 135.5°C
• Density: 1.177g/cm³
• Vapor Pressure: 0.000538mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: (3,4-dimethoxyphenyl)(oxo)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-dimethoxyphenyl)(oxo)acetonitrile(65961-86-6)
• EPA Substance Registry System: (3,4-dimethoxyphenyl)(oxo)acetonitrile(65961-86-6)

Safety Data

• Hazardous Substances Data: 65961-86-6(Hazardous Substances Data)

Usage

General Description

(3,4-dimethoxyphenyl)(oxo)acetonitrile, also known as dimethoxybenzoylacetonitrile, is a chemical compound with the molecular formula C11H11NO3. It is a white to pale yellow crystalline solid that is commonly used as a reagent in organic synthesis and pharmaceutical research. (3,4-dimethoxyphenyl)(oxo)acetonitrile is often employed as an intermediate in the production of various pharmaceutical drugs and agrochemicals. It is also used in the development of new materials and is a valuable building block for the synthesis of more complex organic molecules. Additionally, (3,4-dimethoxyphenyl)(oxo)acetonitrile is known for its potential as a versatile building block for the synthesis of bioactive compounds with various pharmacological properties. However, it is important to handle this compound with care, as it may pose health and environmental hazards if not managed properly.

Upstream product

• 6309-18-8 2-(3,4-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 544-92-3 copper(I) cyanide 
• 74-90-8 hydrogen cyanide 

Downstream Products

• 82461-63-0 C₁₅H₁₄BrNO₄ 
• 93-07-2 Veratric acid 
• 58848-87-6 C₁₁H₁₃N₅O₂ 
• 78004-24-7 (3,4-dimethoxy-phenyl)-acetic acid-(β-hydroxy-3,4-dimethoxy-phenethylamide) 
• 82461-73-2 N-(3,4-Dimethoxy-benzoyloxy)-N-isopropyl-benzamide 
• 82461-72-1 N-tert-Butyl-N-(3,4-dimethoxy-benzoyloxy)-benzamide 
• 82461-67-4 N-(3,4-Dimethoxy-benzoyloxy)-N-phenyl-acetamide 
• 40869-57-6 2-amino-1-(3,4-dimethoxy-phenyl)-ethanone 
• 4732-70-1 3,4-dimethoxyphenylglyoxylic acid 
• 82461-66-3 C₁₂H₁₇NO₄ 
• 82461-59-4 C₁₅H₁₅NO₄ 
• 13546-91-3 N-hydroxy-3,4-dimethoxybenzamide 
• 2024-83-1 veratronitrile 
• 82461-65-2 C₁₃H₁₉NO₄ 

Relevant articles and documents

CYCLIC TRIAZO SODIUM CHANNEL BLOCKERS

The present invention relates to triazine compounds having sodium channel blocking properties, and to use of the compounds for preparation of medicaments for treatment of associated disorders. The compounds are of formula (I): in which z is a single bond

Ruthenium-Catalyzed Oxidations of Alcohols

A combination of low-valent ruthenium complexes and peroxides such as t-BuOOH and peracids serves as efficient catalytic systems for the oxidation of aromatic and aliphatic hydroxy compounds. The utility of these methods was demonstrated by the synthesis of acyl cyanides which are versatile synthetic intermediates. The principle of the catalytic oxidations with peracids lead to the novel and efficient method for aerobic oxidation of alcohols in the presence of aldehydes. This reaction is of importance in synthetic and large scale industrial processes and from environmental points of view. The present principle will provide new chemistry of oxidative transformations of various industrially important functional materials.

RUTHENIUM CATALYZED OXIDATION OF CYANOHYDRINS TO ACYL CYANIDES USEFUL REAGENTS FOR SELECTIVE N-BENZOYLATION OF AMINOALCOHOLS

Ruthenium catalyzed oxidation of cyanohydrins with tert-butyl hydroperoxide gives the corresponding acyl cyanides in good to excellent yields.Acyl cyanides thus obtained are useful reagents for selective N-benzoylation of aminoalcohols.