65964-61-6

Basic information

• Product Name: 7-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine
• Synonyms: 7-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine
• CAS NO: 65964-61-6
• Molecular Formula: C₁₅H₁₄N₂
• Molecular Weight: 222.28506
• Mol File: 65964-61-6.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine(65964-61-6)
• EPA Substance Registry System: 7-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine(65964-61-6)

Safety Data

• Hazardous Substances Data: 65964-61-6(Hazardous Substances Data)

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 619-41-0 4-(bromoacetyl)toluene 
• 122-00-9 para-methylacetophenone 
• 766-97-2 4-n-methylphenylacetylene 
• 13466-41-6 4-methyl-1H-pyridin-2-one 
• 7559-36-6 4-methyl-β-nitrostyrene 
• 108-89-4 picoline 
• 89108-49-6 1-(1-azidovinyl)-4-methyl benzene 
• 33458-08-1 1-(1,2-dibromoethyl)-4-methylbenzene 

Downstream Products

• 65964-50-3 7-(trans-2-thiophen-2-yl-vinyl)-2-p-tolyl-imidazo[1,2-a]pyridine 
• 70013-29-5 4-methyl-N-(4-methylpyridin-2-yl)benzamide 
• 1310492-85-3 7-methyl-3-(phenylthio)-2-(4-methylphenyl)imidazo[1,2-a]pyridine 

Relevant articles and documents

Synthetic method of imidazopyridine compounds

The invention provides a novel method for synthesizing imidazopyridine compounds. According to the invention, aminopyridine compounds and sulfur ylide are used as original reaction substrates, iron phthalocyanine (FeIIPc) is used as a catalyst, and a series of the imidazopyridine compounds are obtained under the condition that the advantages of mildness, greenness, high efficiency, wide substrateuniversality and the like are achieved.

Gold-catalyzed oxidation of terminal alkynes to glyoxals and their reactions with 2-phenylimidazo[1,2-a]pyridines: one-pot synthesis of 1,2-diones

A novel one-pot protocol for the convenient and efficient synthesis of (2-phenylimidazo[1,2-a]pyridin-3-yl)alkane-1,2-diones (3) in good yields (32-88%) from 2-phenylimidazo[1,2-a]pyridines (1) and terminal alkynes (2) has been established with a wide range of substrate scope. A tandem reaction sequence containing gold-catalyzed double oxidations of terminal alkynes to generate glyoxals, nucleophilic addition of 2-phenylimidazo[1,2-a]pyridines to glyoxals to yield α-hydroxyl ketones, and oxygenation of the α-hydroxyl ketones to afford the final products3under air atmosphere is involved in this method. Simple operation, mild reaction conditions, and widely available substrates make this strategy more affordable.

Iodine mediated oxidative cross coupling of 2-aminopyridine and aromatic terminal alkyne: A practical route to imidazo[1,2-: A] pyridine derivatives

A novel, transition-metal free route leading to imidazo[1,2-a]pyridine derivatives via iodine mediated oxidative coupling between 2-aminopyridine and aromatic terminal alkyne has been demonstrated. This newly developed method discloses an operationally simple way for the construction of imidazoheterocycles. Commercially available antiulcer drug zolimidine may readily be synthesized employing this method.