6601-20-3

Usage

Uses

Used in Rubber and Polymer Industry:
N,N'-DIALLYLTHIOUREA is used as a cross-linking agent for improving the strength and durability of rubber and polymer products. Its ability to form covalent bonds between polymer chains contributes to the enhanced mechanical properties and stability of the final products.
Used in Pharmaceutical Research:
N,N'-DIALLYLTHIOUREA is studied as a potential antiviral and antifungal agent due to its capacity to inhibit the growth of certain microorganisms. This makes it a candidate for the development of new treatments against viral and fungal infections.
Used in Radiation Protection Research:
In the field of radiation protection, N,N'-DIALLYLTHIOUREA has shown promise in protecting against radiation-induced DNA damage. This property could be instrumental in the creation of pharmaceuticals aimed at mitigating the harmful effects of radiation exposure, particularly for individuals undergoing radiotherapy or living in high-radiation environments.
While the provided materials do not specify different industries for the uses of N,N'-DIALLYLTHIOUREA, the applications mentioned above are based on the general information provided and can be adapted to specific industries as further research and development progress.

InChI:InChI=1/C7H12N2S/c1-3-5-8-7(10)9-6-4-2/h3-4H,1-2,5-6H2,(H2,8,9,10)

Upstream product

• 13991-81-6 N,N'-bis-(4-dimethylamino-phenyl)-thiourea 
• 57-06-7 N-allyl isothiocyanate 
• 56-89-3 L-cystine 
• 75-15-0 carbon disulfide 
• 25642-42-6 N-allyl-N'-(4,4'-bis-dimethylamino-benzhydrylidene)-thiourea 

Downstream Products

• 57-06-7 N-allyl isothiocyanate 
• 63398-71-0 4-(3-Acetylsulfamoyl-4-chloro-phenyl)-3-allyl-2-allylimino-1,3-thiazolidine-4-ol-hydrobromide 
• 59814-57-2 3-allyl-2-allylimino-4-(4-chloro-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride 
• 63398-76-5 3-Allyl-2-allylimino-4-(4-chloro-3-cyclohexylaminocarbonylsulfamoyl-phenyl)-1,3-thiazolidine-4-ol-hydrobromide 

Relevant academic research and scientific papers

Thermal Degradation of Allyl Isothiocyanate in Aqueous Solution

Allyl isothiocyanate in an aqueous solution was heated and refluxed at 100 °C for 1 h. The reaction mixtures were then extracted with methylene chloride and analyzed using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The mixtures in aqueous phase were analyzed by high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) equipped with an atmospheric-pressure chemical ionization (APCI) interface. The compounds identified in the methylene chloride extracts included diallyl sulfide, diallyl disulfide, diallyl trisulfide, diallyl tetrasulfide, allyl thiocyanate, 3H-1,2-dithiolene, 2-vinyl-4H-1,3-dithiin, 4H-1,2,3-trithiin, and 5-methyl-1,2,3,4-tetrathiane. N,N′-Diallylthiourea, which was the major degradation product in the aqueous phase from the thermal reaction of allyl isothiocyanate, was identified by using LC-MS (APCI+), direct-probe EI-MS, and 1H-NMR. The possible mechanism for the formation of these products was proposed.

Oxidative Scission of the Disulfide Bond of Cystine and Polypeptides by the Action of Allyl Isothiocyanate

The interaction of allyl isothiocyanate (1) with L-cystine and polypeptides under mild conditions was studied in detail.The reaction mixtures composed of isothiocyanate and cystine were incubated at 40, 60 and 80 deg C, in which cystine completely decomposed after 120, 6 and 2 hr, respectively.Degradation products were isolated and identified as 2-allylamino-2-thiazoline-4-carboxylic acid (2), 2-amino-2-thiazoline-4-carboxylic acid (3) and 3(3H)-allyl-5,6-dihydro-5-amino-2(2H)-thioxo-1,3-thiazin-4-one (4).These products were formed through an oxidative acission of the disulfide bond in cystine by the electrophilic attack of allyl isothiocyanate; the products 2 and 4 seemed to be derived through alanyl N-allyldithiocarbamate and the product 3 through β-thiocyanoalanine.In addition, it was confirmed that a part of the disulfide bond in oxidized glutathione and insulin was also cleaved by isothiocyanate.