660425-42-3

Basic information

• Product Name: 3(2H)-Pyridazinone, 5-[3-(3,5-difluoro-2-pyridinyl)-4-fluorophenyl]-
• CAS NO: 660425-42-3
• Molecular Formula: C15H8F3N3O
• Molecular Weight: 303.243
• Mol File: 660425-42-3.mol

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 5-[3-(3,5-difluoro-2-pyridinyl)-4-fluorophenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 5-[3-(3,5-difluoro-2-pyridinyl)-4-fluorophenyl]-(660425-42-3)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 5-[3-(3,5-difluoro-2-pyridinyl)-4-fluorophenyl]-(660425-42-3)

Safety Data

• Hazardous Substances Data: 660425-42-3(Hazardous Substances Data)

Upstream product

• 1993-03-9 o-fluorophenylboronic acid 
• 425379-31-3 2-(5-bromo-2-fluorophenyl)-3,5-difluoropyridine 
• 884863-46-1 3,5-difluoro-2-(2-fluorophenyl)pyridine 
• 660425-16-1 2-bromo-3,5-difluoropyridine 
• 425379-32-4 [3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]boronic acid 

Downstream Products

• 660423-96-1 5-[3-(3,5-difluropyridin-2-yl)-4-fluorophenyl]-3-(2-fluorophenyl)pyridazine 
• 660425-43-4 3-chloro-5-[3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]pyridazine 

Relevant articles and documents

A pyridazine series of α2/α3 subtype selective GABAA agonists for the treatment of anxiety

The development of a series of GABAA α2/α3 subtype selective pyridazine based benzodiazepine site agonists as anxiolytic agents with reduced sedative/ataxic potential is described, including the discovery of 16, a remarkably α3-selective compou

PHENYLPYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

A class of 4-phenylpyridazine derivatives of Formula (I), being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevent