660440-46-0Relevant academic research and scientific papers
Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists
Witherington, Jason,Blaney, Emma L.,Bordas, Vincent,Elliott, Richard L.,Gaiba, Alessandra,Garton, Neil,Green, Philip M.,Naylor, Antoinette,Smith, David G.,Spalding, David J.,Takle, Andrew K.,Ward, Robert W.
, p. 5538 - 5541 (2006)
A series of pyridone-N-benzyl-propanoic acids have been optimised to afford potent orally bioavailable VLA-4 antagonists.
