66046-54-6

Usage

Common Uses

Building block in the synthesis of pharmaceuticals and dyes

Salt of

Triamine compound

Structure

Benzene ring with three amine groups attached

Physical State

Crystalline solid

Solubility

Soluble in water

Applications

a. Biochemical research
b. Drug development
c. Chelating agent in metal ion binding
d. Catalyst in organic synthesis

Importance

Versatile properties in the field of chemistry and pharmaceuticals

Upstream product

• 606-22-4 2,6-dinitroaniline 

Downstream Products

• 16566-20-4 quinoxalin-5-ylamine 
• 792189-09-4 N-acetyl-sulfanilic acid quinoxalin-5-ylamide 
• 137654-47-8 C₈H₇N₃O 
• 767-65-7 4-amino-2,1,3-benzoselenadiazole 
• 861305-18-2 N,N',N''-benzene-1,2,3-triyl-tris-acetamide 
• 4331-29-7 4-aminobenzimidazole 

Relevant academic research and scientific papers

Application of the Gould-Jacobs reaction to 4-amino-2,1,3- benzoselenadiazole

An effective method for the synthesis of 4-amino-2,1,3-benzoselenadiazole (4) has been described. Reduction of readily available 4-nitrobenzothiadiazole 6 with SnCl2·2H2O afforded 1,2,3-triaminobenzene dihydrochloride 2. The latter u

Hydrogenation on palladium-containing granulated catalysts 3. Synthesis of aminobenzimidazoles by catalytic hydrogenation of dinitroanilines

Efficient hydrogenation of o-aminonitrobenzenes on palladium-containing granulated carbon catalysts in carboxylic acid solutions was accompanied by cyclization into aminobenzimidazoles. A simple hydrogenation reactor with a fixed gauze holding a reusable granulated catalyst was designed. Acylated and sulfonylated 4(7)-aminobenzimidazoles were obtained. In terms of electronic and geometrical parameters, they are close analogs of biologically active imidazo[1,5,4-e,f ][1,5]benzodiazepines.